ReviewOncoTargets and therapy2013
Ocular side effects of biological agents in oncology: what should the clinician be aware of?
Review in OncoTargets and therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Ocular Surface Side Effects of Novel Anticancer Drugs.Cancers · 2024Review
- Partial thickness subfoveal hole in a patient treated with tamoxifen: a case report and review of the literature.Journal of medical case reports · 2022Review
- Review
- Ibrutinib-related uveitis: A case series.American journal of ophthalmology case reports · 2022Article
- Human immunocompetent choroid-on-chip: a novel tool for studying ocular effects of biological drugs.Communications biology · 2022Article
- Ocular Toxicity of Targeted Anticancer Agents.Drugs · 2021Review
- Targeted Cancer Therapy and Its Ophthalmic Side Effects: A Review.Journal of immunotherapy and precision oncology · 2021Review
- [Toxic retinopathies].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Article
- Development of a physiologically-based pharmacokinetic model for ocular disposition of monoclonal antibodies in rabbits.Journal of pharmacokinetics and pharmacodynamics · 2020Article
- [Exacerbation of ocular myasthenia gravis].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Article
- Known and novel ocular toxicities of biologics, targeted agents, and traditional chemotherapeutics.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Neuro-ophthalmic side effects of molecularly targeted cancer drugs.Eye (London, England) · 2018Review
- Supportive care for patients undergoing immunotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Ocular Toxicity of Tyrosine Kinase Inhibitors.Oncology nursing forum · 2016Review
- Use of amniotic membrane graft in the surgical management of cicatricial ectropion associated with cetuximab therapy.Journal of surgical case reports · 2015Article
- Vogt-Koyanagi-Harada-Like Disease with Loss of Visual Acuity due to Sunitinib Treatment Restored after Switch in Therapy: A Case Report.Case reports in ophthalmologyArticle
- Ocular adverse effects of therapeutic biologics.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the last 20 years, biologicals have become increasingly relevant in oncologic therapy. Depending on the medication used, there are different profiles of ocular side effects. Although these can be present in up to 70% of patients, they are generally underreported in the literature. Therefore, the pathophysiological details of their development are often poorly understood. Herein we attempt to identify groups of biologicals to which a specific side effect profile can be assigned. We also tried to capture all relevant side effects and therefore conducted several database investigation including Medline, Cochrane library, and the drugs section of the US Food and Drug Administration (FDA), using the following search strings: "name of biological agent (both generic and commercial names)" AND "eye" OR "ocular". If we found a side effect that has been associated with a drug, we researched Medline using the following search string: "name of biological agent" (both generic and commercial names) AND "term for the specific side effect". Due to the wealth of material we report only the drugs that are approved by the FDA.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.