Evidence map›Paper›PMID 24391198›Full record

ArticleJournal of clinical microbiology2014

Comparison of the BD Veritor System for Flu A+B with the Alere BinaxNOW influenza A&B card for detection of influenza A and B viruses in respiratory specimens from pediatric patients.

Ferdaus Hassan, Ashley Nguyen, Ashley Formanek, James J Bell, Rangaraj Selvarangan

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Ecoimmunology in the field: Measuring multiple dimensions of immune function with minimally invasive, field-adapted techniques.American journal of human biology : the official journal of the Human Biology Council · 2022
    Review
  5. Review
  6. Article
  7. Review
  8. Are Rapid Influenza Antigen Tests Still Clinically Useful in Today's Molecular Diagnostics World?Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2018
    Article
  9. Point-of-care diagnostics for respiratory viral infections.Expert review of molecular diagnostics · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Pathology Consultation on Influenza Diagnostics.American journal of clinical pathology · 2016
    Review
  14. Article
  15. Editorial Commentary: Symptoms and Viral Shedding in Naturally Acquired Influenza Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ferdaus HassanDepartment of Pathology and Laboratory Medicine, Children's Mercy Hospitals and Clinics, Kansas City, Missouri, USA.
Ashley Nguyen
Ashley Formanek
James J Bell
Rangaraj Selvarangan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance characteristics of two commercially available rapid tests for influenza, the BD Veritor System for Flu A+B (BD) and the Alere BinaxNOW influenza A&B card (BN), were evaluated using 200 frozen clinical specimens collected from January 2011 to June 2012 from pediatric patients. Real-time reverse transcriptase PCR (RT-PCR) was used as the gold standard to evaluate the results obtained by the two different assays. Of the 200 specimens tested, real-time RT-PCR assay detected influenza A or B virus in 116 samples, while BD detected 104 samples and BN detected 84 samples as positive. The overall sensitivity and specificity for detection of both influenza A and B virus in comparison to those of real-time RT-PCR were 89.6% (95% confidence interval [CI], 82.2 to 94.3) and 98.8% (95% CI, 92.6 to 99.9) for BD Veritor and 72.4% (95% CI, 63.2 to 80.0) and 100% (95% CI, 94.5 to 100.0) for BinaxNOW. Workflow analysis indicated that overall processing times for a batch size of 10 specimens were virtually identical between both systems. Overall, these results indicate that the BD Veritor assay was more sensitive than the BinaxNOW assay in detection of influenza A and B viruses in respiratory specimens from pediatric patients.

Indexed as

AdolescentBodily SecretionsChildChild, PreschoolDiagnostic Tests, RoutineFemaleHumansImmunoassayInfantInfant, NewbornInfluenza A virusInfluenza B virusInfluenza, HumanMaleRespiratory SystemSensitivity and Specificity

Identifiers

PMID24391198
PMCPMC3957768

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.