ArticleClinical and vaccine immunology : CVI2014
High-throughput assay optimization and statistical interpolation of rubella-specific neutralizing antibody titers.
Article in Clinical and vaccine immunology : CVI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Comparative Antibody Responses to the Live-Attenuated and Recombinant Herpes Zoster Vaccines.Journal of virology · 2021Trial
- Measles and rubella: From global health challenges to advancements in molecular diagnostics in the elimination era.Molecular therapy. Nucleic acids · 2025Review
- Serosurveillance for Measles and Rubella.Vaccines · 2024Review
- Long-term Neutralizing Antibody Levels Against Measles and Rubella Viruses Among Adults With 3 Doses of Measles-Mumps-Rubella Vaccine.Open forum infectious diseases · 2024Article
- Associations of adaptive immune cell subsets with measles, mumps, and Rubella-Specific immune response outcomes.Heliyon · 2023Article
- Transcriptional signatures associated with rubella virus-specific humoral immunity after a third dose of MMR vaccine in women of childbearing age.European journal of immunology · 2021Article
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- Measles and rubella IgG seroprevalence in persons 6 month-35 years of age, Mongolia, 2016.Vaccine · 2020Article
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- Seroprevalence and durability of rubella virus antibodies in a highly immunized population.Vaccine · 2019Article
- Characterization of rubella-specific humoral immunity following two doses of MMR vaccine using proteome microarray technology.PloS one · 2017Article
- Assessing Immunity to Rubella Virus: a Plea for Standardization of IgG (Immuno)assays.Journal of clinical microbiology · 2016Article
- Zika Virus: A New Animal Model for an Arbovirus.PLoS neglected tropical diseases · 2016Article
- Single nucleotide polymorphisms/haplotypes associated with multiple rubella-specific immune response outcomes post-MMR immunization in healthy children.Immunogenetics · 2015Article
- Rubella.Lancet (London, England) · 2015Review
- Polymorphisms in HLA-DPB1 are associated with differences in rubella virus-specific humoral immunity after vaccination.The Journal of infectious diseases · 2015Article
- Single-nucleotide polymorphism associations in common with immune responses to measles and rubella vaccines.Immunogenetics · 2014Article
- Associations between race, sex and immune response variations to rubella vaccination in two independent cohorts.Vaccine · 2014Article
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Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Rubella remains a social and economic burden due to the high incidence of congenital rubella syndrome (CRS) in some countries. For this reason, an accurate and efficient high-throughput measure of antibody response to vaccination is an important tool. In order to measure rubella-specific neutralizing antibodies in a large cohort of vaccinated individuals, a high-throughput immunocolorimetric system was developed. Statistical interpolation models were applied to the resulting titers to refine quantitative estimates of neutralizing antibody titers relative to the assayed neutralizing antibody dilutions. This assay, including the statistical methods developed, can be used to assess the neutralizing humoral immune response to rubella virus and may be adaptable for assessing the response to other viral vaccines and infectious agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.