Evidence map›Paper›PMID 24390980›Full record

ArticleJournal of medical virology2014

Human bocavirus isolated from children with acute respiratory tract infections in Korea, 2010-2011.

Jong Gyun Ahn, Seong Yeol Choi, Dong Soo Kim, Ki Hwan Kim

Abstract read
In one paragraph

Article in Journal of medical virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Respiratory viral coinfection and disease severity in children: A systematic review and meta-analysis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016
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  11. Circulation profile of respiratory viruses in symptomatic and asymptomatic children from Midwest Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  12. Human Bocavirus infection and respiratory tract disease identified in a UK patient cohort.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jong Gyun AhnDepartment of Pediatrics, School of Medicine, Ewha Womans University, Seoul, Korea; Department of Medicine, The Graduate School of Yonsei University, Seoul, Korea.
Seong Yeol Choi
Dong Soo Kim
Ki Hwan Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 children with acute respiratory infections between 2010 and 2011. Respiratory samples were screened for HBoV by multiplex PCR. A phylogenetic analysis of the HBoV VP1/VP2 gene was also undertaken. HBoV was detected in 187 (12.2%) of the 1,528 patients with a peak incidence of infection observed in patients aged 12-24 months. Coinfection with other respiratory viruses was observed in 107 (57.2%) of the HBoV-positive children. The peak of HBoV activity occurred during the month of June in both 2010 and 2011. A higher previous history of wheezing (P = 0.016), a higher frequency of chest retraction (P < 0.001) and wheezing (P = 0.022), a higher respiratory symptom score (P = 0.002), and a longer duration of hospital stay (P = 0.021) were observed in HBoV-positive children compared with the HBoV-negative group. Phylogenetic analysis showed all 187 HBoV-positive isolates were identified as HBoV 1, indicating minimal sequence variations among the isolates. A single lineage of HBoV 1 was found to have circulated in children with acute respiratory infections between 2010 and 2011 and was associated with several clinical characteristics including age, seasonality, and clinical severity with retraction, wheezing, and longer hospitalization. The clinical relevance of the minimal sequence variations of HBoV remains to be determined.

Indexed as

ChildChild, PreschoolCluster AnalysisCoinfectionDNA, ViralFemaleGenetic VariationGenotypeHuman bocavirusHumansInfantMaleMolecular Sequence DataMultiplex Polymerase Chain ReactionNasopharynxParvoviridae InfectionsDNA, ViralViral Structural Proteinsacute respiratory infectionshuman bocavirusphylogenetic analysis

Identifiers

PMID24390980
PMCPMC7166562

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.