ReviewSeminars in reproductive medicine2014
Fetal immune response to chorioamnionitis.
Review in Seminars in reproductive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
75 citing papers in PubMed, 117 citations in OpenAlex.
- Can prenatal conditions impact the effect of omega-3 on bronchopulmonary dysplasia in very preterm infants? A secondary analysis of a randomized controlled trial.European journal of pediatrics · 2025Trial
- Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth.Journal of immunology (Baltimore, Md. : 1950) · 2019Trial
- Histologic chorioamnionitis in preterm infants: correlation with brain magnetic resonance imaging at term equivalent age.BMC pediatrics · 2018Trial
- Stem cells redirect the neuroinflammatory trajectory of primed microglia in an ovine chorioamnionitis model.Brain, behavior, & immunity - health · 2026Article
- Chorioamnionitis and Neonatal Morbidity and Mortality in Extremely Preterm Infants Born at 23-28 Weeks: A Single-Centre Retrospective Study.Journal of clinical medicine · 2026Article
- Maternal-fetal dialogue and immunological programming: from fetal development to long-term health outcomes.Frontiers in oncology · 2026Review
- Use of hydrocortisone in extremely preterm infants: emphasis on those born least mature.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Impact of intraamniotic inflammation on tryptophan metabolism in the placenta-fetal brain axis in rats.Reproduction (Cambridge, England) · 2025Article
- Systemic inflammatory responses to repeated and increasing endotoxin challenges in fetal sheep.Physiological reports · 2025Article
- Neurodevelopmental outcomes in extremely preterm infants with placental pathologic evidence of fetal inflammatroy response.Pediatric research · 2025Article
- Small Extracellular Vesicles Derived from Cord Blood Plasma and Placental Mesenchymal Stem Cells Attenuate Acute Lung Injury Induced by Lipopolysaccharide (LPS).International journal of molecular sciences · 2024Article
- Expression of Leukemia Inhibitory Factor (LIF) and p53 on Human Fetal Lung After Chorioamnionitis Suffering.Cureus · 2024Article
- Fetal origin of bronchopulmonary dysplasia: contribution of intrauterine inflammation.Molecular medicine (Cambridge, Mass.) · 2024Review
- Mild/asymptomatic COVID-19 in unvaccinated pregnant mothers impairs neonatal immune responses.JCI insight · 2023Article
- The Role of Infection and Inflammation in the Pathogenesis of Pediatric Arterial Ischemic Stroke.Seminars in pediatric neurology · 2022Review
- A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation.Mucosal immunology · 2022Article
- Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates.Science translational medicine · 2022Article
- Placental mediated mechanisms of perinatal brain injury: Evolving inflammation and exosomes.Experimental neurology · 2022Review
- Understanding the Immune System in Fetal Protection and Maternal Infections during Pregnancy.Journal of immunology research · 2022Review
- Effects of maternal ritodrine hydrochloride administration on the heart rate of preterm fetal sheep with intraamniotic inflammation.PloS one · 2022Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Chorioamnionitis is a frequent cause of preterm birth and is associated with an increased risk for injury responses in the lung, gastrointestinal tract, brain, and other fetal organs. Chorioamnionitis is a polymicrobial nontraditional infectious disease because the organisms causing chorioamnionitis are generally of low virulence and colonize the amniotic fluid often for extended periods, and the host (mother and the fetus) does not have typical infection-related symptoms such as fever. In this review, we discuss the effects of chorioamnionitis in experimental animal models that mimic the human disease. Our focus is on the immune changes in multiple fetal organs and the pathogenesis of chorioamnionitis-induced injury in different fetal compartments. As chorioamnionitis disproportionately affects preterm infants, we discuss the relevant developmental context for the immune system. We also provide a clinical context for the fetal responses.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.