ArticlePrevention science : the official journal of the Society for Prevention Research2014
Preventing internalizing symptoms among Hispanic adolescents: a synthesis across Familias Unidas trials.
Article in Prevention science : the official journal of the Society for Prevention Research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed.
- Familias Unidas Prevents Youth Internalizing Symptoms: a Baseline Target Moderated Mediation (BTMM) Study.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Emotion Regulation Difficulties in Military Fathers Magnify Their Benefit from a Parenting Program.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Results of a Family-Based Intervention Promoting Healthy Weight Strategies in Overweight Hispanic Adolescents and Parents: An RCT.American journal of preventive medicine · 2020Trial
- A Culturally Adapted Intervention for Mexican-Origin Parents of Adolescents: The Need to Overtly Address Culture and Discrimination in Evidence-Based Practice.Family process · 2019Trial
- Examining the impact of differential cultural adaptation with Latina/o immigrants exposed to adapted parent training interventions.Journal of consulting and clinical psychology · 2017Trial
- Reducing Internalizing Symptoms Among High-Risk, Hispanic Adolescents: Mediators of a Preventive Family Intervention.Prevention science : the official journal of the Society for Prevention Research · 2016Trial
- Reducing the Risk of Internalizing Symptoms among High-risk Hispanic Youth through a Family Intervention: A Randomized Controlled Trial.Family process · 2016Trial
- Preventing adolescent depression with the family check-up: Examining family conflict as a mechanism of change.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2016Trial
- Changing Latino Adolescents' Substance Use Norms and Behaviors: the Effects of Synchronized Youth and Parent Drug Use Prevention Interventions.Prevention science : the official journal of the Society for Prevention Research · 2016Trial
- Annual Research Review: Beyond the target - understanding crossover effects in family-centered prevention.Journal of child psychology and psychiatry, and allied disciplines · 2026Review
- Development of a family functioning measure for Hispanic lesbian, gay, and bisexual adolescents.Frontiers in public health · 2026Article
- Depressive Symptoms Over the Course of Adolescence Among Latinx Children of Immigrants and Non-Immigrants and White Youth From Small Towns in the United States.Child & youth care forum · 2025Article
- Intergenerational continuity of adverse childhood experiences among Mexican-origin families: Examination of intra and extra-familial adversities.Family process · 2025Article
- Adaptation of an evidence-based, preventive intervention to promote mental health in Hispanic adolescents: eHealth Familias Unidas Mental Health.Translational behavioral medicine · 2024Article
- Screening for Adolescent Risk Behaviors: Preliminary Evidence for a Family Functioning Tool.International journal of behavioral medicine · 2024Article
- Parental psychopathology and posttraumatic stress in Puerto Ricans: the role of childhood adversity and parenting practices.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Multiple Perspectives on Motivating Parents in Pediatric Primary Care to Initiate Participation in Parenting Programs.Academic pediatrics · 2024Article
- Strategic Directions in Preventive Intervention Research to Advance Health Equity.Prevention science : the official journal of the Society for Prevention Research · 2023Review
- Family Functioning in Hispanic Parents of Adolescents: Who Benefits Most from a Family-Based HIV and Substance Use Preventive Intervention?Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Estimating latent baseline-by-treatment interactions in statistical mediation analysis.Structural equation modeling : a multidisciplinary journal · 2023Article
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Authors and funding
9 authors.
Funding
Abstract
Studies document that there are efficacious interventions to prevent adolescent depression and internalizing symptoms, including several family-focused interventions. Questions remain about for whom interventions work (moderation) and by what mechanisms they work (mediation) to prevent internalizing symptoms. Unfortunately, single trials are often underpowered to address moderation and mediation, an issue addressed in this paper. This synthesis study combined individual-level, longitudinal data from 721 adolescents across 3 randomized clinical trials of Familias Unidas, a family-focused prevention intervention for Hispanic youth. Using integrative data analysis (IDA) methods applied to trials, the study examined intervention moderation and mediation effects on internalizing symptoms. Baseline internalizing symptoms were a significant moderator of the intervention's effects on internalizing symptoms, while baseline externalizing symptoms did not moderate intervention effects. Baseline parent-adolescent communication, a modifiable risk factor and hypothesized mechanism by which the intervention works, significantly moderated the intervention's effects. Specifically, the intervention was more efficacious in its impact on internalizing symptoms for youth with lower initial levels of parent-adolescent communication compared to those with higher communication levels. Moderated mediation analyses showed that parent-adolescent communication changes mediated the intervention's effects on internalizing symptoms, with stronger effects for those with poorer baseline communication. Results suggest a potential benefit of identifying youth risks prior to interventions, and targeting specific modifiable mediators that lead to reductions of internalizing problems of adolescents. Findings also highlight advantages of utilizing data from combined trials and IDA for examining intervention moderators and mediators.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.