ArticleJapanese journal of ophthalmology2014
Incidence of deepening of the upper eyelid sulcus on treatment with a tafluprost ophthalmic solution.
Article in Japanese journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07074782 (Retinal Ganglion Cell Neuroprotection Under Prostaglandin Analogues), which is not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Retinal Ganglion Cell Neuroprotection Under Prostaglandin Analogues: NEUROPA - a Retrospective Cohort Study
Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Impact of prostaglandin-associated periorbitopathy on surgical outcomes of trabeculectomy and ahmed glaucoma valve implantation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- The Usefulness of Inclusion of Visual Field Tests Using Multiple Testing Strategies in Perimetric Rate of Progression Analyses.Translational vision science & technology · 2025Article
- The Effect of Preoperative Use of High- vs. Low-PAP-Inducing-Potential FP Agonists on the Surgical Outcomes of Trabeculectomy and AGV Implantation.Journal of clinical medicine · 2025Article
- Evaluation of the Effect of Topical Prostaglandin Analog Treatment on Orbital Structures in Open-Angle Glaucoma with Computed Tomography.Journal of clinical medicine · 2024Article
- Improvement of Prostaglandin-Associated Periorbitopathy after Discontinuing Treatment.Turkish journal of ophthalmology · 2023Article
- The number of examinations required for the accurate prediction of the progression of the central 10-degree visual field test in glaucoma.Scientific reports · 2022Article
- Shortening of interpupillary distance after topical prostaglandin analog eye drop application in an ophthalmic surgeon: A case report.American journal of ophthalmology case reports · 2022Article
- Prostanoid receptor agonists for glaucoma treatment.Japanese journal of ophthalmology · 2021Review
- Recovery of deepening of the upper eyelid sulcus after switching from prostaglandin FP receptor agonists to EP2 receptor agonist: a 3-month prospective analysis.Japanese journal of ophthalmology · 2021Observational
- Decreased orbital fat and enophthalmos due to bimatoprost: Quantitative analysis using magnetic resonance imaging.PloS one · 2019Observational
- Treatment with bimatoprost for exophthalmos in patients with inactive thyroid-associated ophthalmopathy.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Periorbital changes associated with prostaglandin analogs in Korean patients.BMC ophthalmology · 2017Article
- Tafluprost Ophthalmic Solution 0.0015 %: A Review in Glaucoma and Ocular Hypertension.Clinical drug investigation · 2016Review
- Prostaglandin-associated periorbitopathy.Indian journal of ophthalmology · 2016Article
- Twenty-four-hour efficacy of preservative-free tafluprost for open-angle glaucoma patients, assessed by home intraocular pressure (Icare-ONE) and blood-pressure monitoring.Japanese journal of ophthalmology · 2016Article
- Prostaglandin-associated periorbitopathy in latanoprost users.Clinical ophthalmology (Auckland, N.Z.) · 2015Article
- Incidence of deepening of the upper eyelid sulcus in prostaglandin-associated periorbitopathy with a latanoprost ophthalmic solution.Eye (London, England) · 2014Article
- Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDeepening of the upper eyelid sulcus (DUES), one symptom of prostaglandin-associated periorbitopathy, was recently found to be an additional side effect of prostaglandin-related ophthalmic solutions. Here, we prospectively investigated the incidence and factors associated with DUES in Japanese open-angle glaucoma patients initially treated with benzalkonium chloride (BAK)-preserved tafluprost (TAF).
methodsIn this open-label prospective study instilling TAF in one eye, mean deviation (MD) and intraocular pressure (IOP) were measured, and facial photographs and subjective reports of DUES were obtained at intervals over 6 months. Three ophthalmologists independently assessed the photographs of DUES and reached consensus. Relationships between demographic and ocular/systemic factors (age, sex, MD, refraction and IOP reduction) and DUES occurrence were evaluated.
resultsForty-three eyes of 43 glaucoma patients (24 men and 19 women) were evaluated. Mean IOP before treatment was 16.6 ± 2.7 and after treatment, 14.1 ± 2.3 mmHg (P < 0.001). The objective rate of DUES was 9 % (4/43) at 2 months, 14 % (6/43) at 4 months and 14 % (6/43) at 6 months. During this period, only one patient self-reported an occurrence of DUES. No significant association was found between DUES occurrence and any of the demographic, ocular, or systemic factors.
conclusionsPhysicians should inform patients about DUES as a minor side effect when prescribing TAF for IOP control.
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