Evidence map›Paper›PMID 24389259›Full record

ReviewFrontiers in bioscience (Scholar edition)2014

Maintaining the reproductive potential of cancer patients during cancer treatment.

Djana Harp, Indrajit Chowdhury, Minerva Garcia-Barrio, Crystal Welch, Roland Matthews, Winston Thompson

Abstract readReview
In one paragraph

Review in Frontiers in bioscience (Scholar edition), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Djana HarpDepartment of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, S.W., Atlanta, GA 30310.
Indrajit ChowdhuryDepartment of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, S.W., Atlanta, GA 30310.
Minerva Garcia-BarrioCardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310.
Crystal WelchDepartment of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, S.W., Atlanta, GA 30310.
Roland MatthewsDepartment of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, S.W., Atlanta, GA 30310.
Winston ThompsonDepartment of Obstetrics and Gynecology, Morehouse School of Medicine, 720 Westview Drive, S.W., Atlanta, GA 30310.

Funding

TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI ZHAO, XUEYING · 1986 to 2011
$32.4M
TRANSPLANTATION OF EXOSOMES FROM HYPOXIA-PRECONDITIONED ADIPOSE-DERIVED STEM CELLS PROMOTES ANGIOGENESIS IN ISCHEMIC HEARTG12MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI BOND, VINCENT C · 2012 to 2017
$18.4M
Renewal Application for Clinical Research Education and Career Development (CRECDR25RR017694 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI OFILI, ELIZABETH O. · 2002 to 2011
$5.5M
Achaete-scute-like-3 (ASCL3) Regulates Vascular Muscle Cell ProliferationSC1HL095099 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI GARCIA-BARRIO, MINERVA T · 2008 to 2011
$1.1M
Neuregulin-1 (NRG1) in preovulatory granulosa cell survival and anti-inflammatory roleSC3GM113751 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI CHOWDHURY, INDRAJIT · 2015 to 2017
$318k
NCRR NIH HHS 2R25RR017694-06ANCRR NIH HHS G12 RR003034NCRR NIH HHS R25 RR017694NHLBI NIH HHS SC11SC1HL095099NHLBI NIH HHS SC1 HL095099NIGMS NIH HHS SC3 GM113751NIMHD NIH HHS 8G12MD007602NIMHD NIH HHS G12 MD007602
6 · The paper itself

Abstract

Cancer therapies are known to alter the reproductive potential in cancer patients. Due to improved survival rates in cancer patients of reproductive age, considerations of the long-term effects of cancer therapy have become more significant. Oncofertility is a new discipline in medicine that deals with maintaining the reproductive potential of cancer patients while they are receiving gonadotoxic cancer treatment. The purpose of this review is to explore how cancer treatment impairs reproductive functioning and present the current options for preservation of fertility in women. All patients with reproductive potential should be made aware of the possible treatment-related infertility and be offered appropriate fertility preservation options before cancer treatment is instituted. The hope is that, in the future, mechanism(s) can be developed to preserve immature germ cells in the ovary, so that they can be used for fertilization in vivo or in vitro.

Indexed as

AdultFemaleFertility PreservationGenital Neoplasms, FemaleHumansInfertility, FemaleNeoplasms

Identifiers

PMID24389259
PMCPMC6178803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.