ReviewFrontiers in bioscience (Elite edition)2014
Polycystic ovary syndrome: current status and future perspective.
Review in Frontiers in bioscience (Elite edition), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03151005 (Randomized Clinical Trial to Evaluate The Effect of Metformin-GLP-1 Receptor Agonist Versus Oral Contraceptive), which is not on this map. Cited by 98 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Clinical Trial to Evaluate The Effect of Metformin-GLP-1 Receptor Agonist Versus Oral Contraceptive (OC) Therapy on Reproductive Disorders and Cardiovascular Risks in Overweight Polycystic Ovarian Syndrome (PCOS) Patients
Who cites it
98 citing papers in PubMed, 1 synthesis or guideline pooled it, 248 citations in OpenAlex.
- Benefits of physical activity on reproductive health functions among polycystic ovarian syndrome women: a systematic review.BMC public health · 2023Pooled it
- Trial
- GDF-15 levels in patients with polycystic ovary syndrome treated with metformin: a combined clinical and in silico pathway analysis.Archives of endocrinology and metabolism · 2024Trial
- Randomized Controlled Trial of Neurokinin 3 Receptor Antagonist Fezolinetant for Treatment of Polycystic Ovary Syndrome.The Journal of clinical endocrinology and metabolism · 2021Trial
- Article
- Polyendocrine metabolic ovarian syndrome (PMOS)/polycystic ovary syndrome (PCOS): current and future trends.The Journal of clinical investigation · 2026Review
- Polycystic Ovary Syndrome (PCOS): A Comprehensive Review of Clinical Approaches, Functional Bioactives, and Nutritional Interventions.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Global Burden of Polycystic Ovary Syndrome: A Systematic Analysis of Pre- and Post-Pandemic Trends from the 2021 Global Burden of Disease Study (1990-2021).International journal of women's health · 2026Article
- Unraveling the Nutritional Perspectives of Probiotics and Prebiotics in Female Healthcare.Recent advances in food, nutrition & agriculture · 2026Review
- Polycystic Ovary Syndrome Revisited: Novel Insights and Updates.International journal of medical sciences · 2026Review
- Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos.Frontiers in genetics · 2026Article
- A review on herbal interventions and nanotechnological advancements for managing polycystic ovarian syndrome.JBRA assisted reproduction · 2025Review
- Insulin resistance in polycystic ovary syndrome phenotypes and the vicious cycle model in its etiology.Scientific reports · 2025Observational
- Effects of Pomegranate Juice on Androgen Levels, Inflammation and Lipid Profile in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Decoding androgen excess in polycystic ovary syndrome: Roles of insulin resistance and other key intraovarian and systemic factors.World journal of diabetes · 2025Review
- Investigation of Inflammatory Markers in Patients with Polycystic Ovary Syndrome Receiving and Not Receiving Metformin Treatment.Medicina (Kaunas, Lithuania) · 2025Article
- Polycystic Ovary Syndrome, Metabolic Syndrome, and Inflammation in the Hispanic Community Health Study/Study of Latinos.The Journal of clinical endocrinology and metabolism · 2025Observational
- Impact of Metformin Therapy on Chronic Inflammatory Markers Serum Fractalkine and CRP Levels in Polycystic Ovary Syndrome: A Pilot Study on Chronic Inflammatory Markers and Clinical Outcomes.Journal of obstetrics and gynaecology of India · 2025Article
- The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank.BMC public health · 2025Article
- Development of machine learning models for diagnostic biomarker identification and immune cell infiltration analysis in PCOS.Journal of ovarian research · 2025Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Polycystic ovary syndrome (PCOS) is a widespread reproductive disorder that encompasses many associated health conditions and has an impact on various metabolic processes. PCOS is depicted by hyperandrogenism, polycystic ovaries, and anovulation. It increases the risk of insulin resistance (IR), type 2 diabetes, obesity, and cardiovascular disease. The etiology of the disease remains unclear, and the subjective phenotype makes a united diagnosis difficult among physicians. It seems to be a familial genetic syndrome caused by a combination of environmental and genetic factors. It can be linked with metabolic disorders in first-degree family members. PCOS is the cause of up to 30% of infertility in couples seeking treatment. Currently, there is no cure for PCOS. Despite the growing incidence of this syndrome, limited research has been done that encompasses the entirety of PCOS spectrum. In this review, the current status and possible future perspective will be discussed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.