Evidence map›Paper›PMID 24388166›Full record

ArticleJournal of biomechanics2014

Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis.

Claire Robertson, Andrew E Heidari, Zhongping Chen, Steven C George

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomechanics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Claire RobertsonDepartment of Biomedical Engineering, University of California, Irvine, 2121 Engineering Hall, Irvine, CA 92617, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, USA.
Andrew E HeidariDepartment of Biomedical Engineering, University of California, Irvine, 2121 Engineering Hall, Irvine, CA 92617, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, USA; Beckman Laser Institute, University of California, Irvine, CA 92617, USA.
Zhongping ChenDepartment of Biomedical Engineering, University of California, Irvine, 2121 Engineering Hall, Irvine, CA 92617, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, USA; Beckman Laser Institute, University of California, Irvine, CA 92617, USA.
Steven C GeorgeDepartment of Biomedical Engineering, University of California, Irvine, 2121 Engineering Hall, Irvine, CA 92617, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, USA; Department of Chemical Engineering, University of California, Irvine, CA 92617, USA; Department of Medicine, University of California, Irvine, CA 92617, USA. Electronic address: scgeorge@uci.edu.
Edwards Lifesciences (United States) · USUniversity of California, Irvine · US

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI BOTVINICK, ELLIOT LAWRENCE · 2012 to 2017
$7.0M
Mechanisms of Subepithelial Fibrosis in AsthmaR01HL067954 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GEORGE, STEVEN CARL · 2003 to 2012
$3.7M
Integrated multi-modality intravascular US/OCT imaging systemR01EB010090 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING · 2009 to 2012
$2.3M
NHLBI NIH HHS R01 HL067954NHLBI NIH HHS R01HL067954NIBIB NIH HHS P41 EB015890NIBIB NIH HHS R01 EB010090NIBIB NIH HHS R01EB010090
6 · The paper itself

Abstract

The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.

Indexed as

AgedAged, 80 and overCadaverCalcinosisComplianceFemaleFemoral ArteryHumansMalePlaque, AtheroscleroticSensitivity and SpecificityTomography, Optical CoherenceYoung AdultAtherosclerotic plaqueComplianceOptical coherence tomography

Identifiers

PMID24388166
PMCPMC3914757
OpenAlexW2122969364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.