Evidence map›Paper›PMID 24387999›Full record

ArticleSchizophrenia research2014

Prodromal psychosis detection in a counseling center population in China: an epidemiological and clinical study.

Tianhong Zhang, Huijun Li, Kristen A Woodberry, Larry J Seidman, Lina Zheng, Hui Li, Shanshan Zhao, Yingying Tang, Qian Guo, Xi Lu and 7 more

Abstract read
In one paragraph

Article in Schizophrenia research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Tianhong ZhangShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Huijun LiFlorida A&M University, Department of Psychology, Tallahassee, FL 32307, USA; Harvard Medical School, Department of Psychiatry, Beth Israel Deaconess Medical Center, 75 Fenwood Rd, Boston, MA 02115, USA.
Kristen A WoodberryHarvard Medical School, Department of Psychiatry, Beth Israel Deaconess Medical Center, 75 Fenwood Rd, Boston, MA 02115, USA.
Larry J SeidmanHarvard Medical School, Department of Psychiatry, Beth Israel Deaconess Medical Center, 75 Fenwood Rd, Boston, MA 02115, USA.
Lina ZhengLiaocheng People's Hospital, Shandong, PR China.
Hui LiShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Shanshan ZhaoShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Yingying TangShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Qian GuoShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Xi LuShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Kaiming ZhuoShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Zhenying QianShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Annabelle ChowChangi General Hospital, Department of Psychological Medicine, Singapore.
Chunbo LiShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Kaida JiangShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China.
Zeping XiaoShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China. Electronic address: xiao_zeping@126.com.
Jijun WangShanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai 200030, PR China. Electronic address: jijunwang27@gmail.com.
Shanghai Mental Health Center · CNHarvard University · USBeth Israel Deaconess Medical Center · USChangi General Hospital · SGLiaocheng People's Hospital · CN

Funding

Training Program in International Mental HealthD43TW005809 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GOOD, BYRON J. · 2001 to 2010
$2.3M
Broadening the Investigation of Psychosis Prodrome to Different Cultural GroupsR21MH093294 · NIMH · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI LI, HUIJUN, SEIDMAN, LARRY J · 2012 to 2013
$249k
FIC NIH HHS D43 TW005809NIMH NIH HHS 1R21 MH093294-01A1NIMH NIH HHS R21 MH093294
6 · The paper itself

Abstract

backgroundTo investigate through a two-stage clinic-based screening, the frequency and clinical features of risk for psychosis syndromes in a Chinese help-seeking sample.

method2101 consecutive new patients ages 15-45 were recruited at their first visit to the Shanghai Mental Health Center (SMHC) and screened with the Prodromal Questionnaire-Brief version (PQ-B) and questions about genetic risk. The Structured Interview for Prodromal Syndromes (SIPS) was administered to a sub-sample to estimate rates of psychosis and clinical high risk (CHR) for psychosis syndromes.

resultsThe frequency estimate of CHR syndromes in the total sample was 4.2%. Among 89 CHR patients, more than two-thirds met the criteria for Attenuated Positive Symptom Syndrome (APSS); and nearly a quarter met the criteria for Genetic Risk and Deterioration Syndrome (GRDS). The frequency of CHR syndromes peaked between the ages of 16 and 21years old and declined with subsequent age. The mean total and distress scores on the PQ-B in subjects with APSS and psychosis were significantly higher than in individuals with GDRS and patients without psychosis or CHR. High frequencies and strong correlations were found among some positive and non-specific symptoms in SIPS interviews. Among the 53 CHR participants who were followed-up for two years, 14 (26.4%) converted to psychosis. Of the non-converters, 53.8% were diagnosed with Axis I disorders.

conclusionsThis two stage screening method can enhance detection of Chinese CHR patients in clinical settings. The validity of the procedures for detecting CHR is supported by rates of transition to psychosis and of non-converter Axis I disorders that are comparable to those reported in meta-analyses.

Indexed as

CounselingProdromal SymptomsAdolescentAdultAge FactorsChinaFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesPsychotherapyPsychotic DisordersStatistics, NonparametricSurveys and QuestionnairesYoung AdultClinical high riskEarly detectionEpidemiologyHelp-seekingUltra-high risk

Identifiers

PMID24387999
PMCPMC4441955
OpenAlexW1999757758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.