Evidence map›Paper›PMID 24387979›Full record

ArticleComprehensive psychiatry2014

Trauma exposure, posttraumatic stress disorder and risk for alcohol, nicotine, and marijuana dependence in Israel.

Kate Walsh, Jennifer C Elliott, Dvora Shmulewitz, Efrat Aharonovich, Rael Strous, Amos Frisch, Abraham Weizman, Baruch Spivak, Bridget F Grant, Deborah Hasin

Abstract read
In one paragraph

Article in Comprehensive psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  10. [Comorbidity of posttraumatic stress disorder and addiction from a biopsychosocial perspective].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kate WalshDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA.
Jennifer C ElliottDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA.
Dvora ShmulewitzDepartment of Psychiatry, Columbia University Medical Center, New York, New York 10032, USA; New York State Psychiatric Institute, New York, New York 10032, USA.
Efrat AharonovichDepartment of Psychiatry, Columbia University Medical Center, New York, New York 10032, USA; New York State Psychiatric Institute, New York, New York 10032, USA.
Rael StrousSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 69978.
Amos FrischSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 69978; Felsenstein Medical Research Center, Petach Tikva, Israel, 49100.
Abraham WeizmanSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 69978; Felsenstein Medical Research Center, Petach Tikva, Israel, 49100; Research Unit, Geha Mental Health Center, Petach Tikva, Israel, 49100.
Baruch SpivakSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 69978.
Bridget F GrantLaboratory of Epidemiology and Biometry, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland, USA.
Deborah HasinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA; Department of Psychiatry, Columbia University Medical Center, New York, New York 10032, USA; New York State Psychiatric Institute, New York, New York 10032, USA. Electronic address: dsh2@columbia.edu.

Funding

National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) - IIIZIAAA000449 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GRANT, BRIDGET F · 2009 to 2016
$16.5M
Substance Abuse Epidemiology Training Program (SAETP) at Columbia UniversityT32DA031099 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DEBORAH S HASIN, Silvia Saboia Martins · 2012 to 2026
$6.1M
Alcohol in Israel: Genetic and Environmental EffectsR01AA013654 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S. · 2003 to 2007
$4.6M
Epidemiologic Studies of Alcohol Use Disorders (ongoing)K05AA014223 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HASIN, DEBORAH S · 2003 to 2012
$1.5M
Cognition in Cocaine Dependence: Assessment &TherapyK23DA016743 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AHARONOVICH, EFRAT · 2003 to 2007
$802k
NIAAA NIH HHS K05 AA014223NIAAA NIH HHS K05AA014223NIAAA NIH HHS R01 AA013654NIAAA NIH HHS R01AA013654NIDA NIH HHS K23 DA016743NIDA NIH HHS K23DA016743NIDA NIH HHS L30 DA036213NIDA NIH HHS T32 DA031099NIDA NIH HHS T32DA031099
6 · The paper itself

Abstract

backgroundSubstance dependence is more common among trauma-exposed individuals; however, most studies suggest that Posttraumatic Stress Disorder (PTSD) accounts for the link between trauma exposure (TE) and substance dependence.

objectivesThis study examined associations between TE and substance dependence (alcohol, nicotine, and marijuana), and whether PTSD accounted for this association.

method1317 Jewish Israeli household residents completed in-person structured interviews assessing TE, PTSD, and substance (alcohol, nicotine, marijuana) dependence between 2007 and 2009. Regression analyses examined associations among TE, PTSD, and substance dependence.

resultsIn the full sample, mean number of traumatic events was 2.7 (sd=2.2), with 83.7% experiencing at least one event. In the full sample, mean number of PTSD symptoms was 2.5 (sd=3.4), with 13.5% meeting PTSD diagnostic criteria. Prevalence of alcohol dependence was 13.4%; nicotine dependence 52.8%; and marijuana dependence 12.1%. Number of traumatic events was associated with increased odds of alcohol (OR=1.3; 95% CI=1.2-1.4) and nicotine (OR=1.2; 95% CI=1.1-1.3) dependence. Similarly, any traumatic event exposure was associated with increased odds of alcohol (OR=3.1; 95% CI=1.6-6.0) and nicotine (OR=1.9; 95% CI=1.2-2.9) dependence. PTSD symptoms were associated with increased odds of alcohol (OR=1.2; 95% CI=1.1-1.3), nicotine (OR=1.1; 95% CI=1.1-1.2), and marijuana (OR=1.1; 95% CI=1.04-1.2) dependence; similarly, a PTSD diagnosis was associated with increased odds of alcohol (OR=3.4; 95% CI=2.1-5.5), nicotine (OR=2.2; 95% CI=1.4-3.4), and marijuana (OR=2.6; 95% CI=1.2-5.9) dependence. PTSD symptoms accounted for a sizeable proportion of the TE effect on alcohol (46%) and nicotine dependence (31%).

conclusionIndividuals with more traumatic events had heightened risk for alcohol and nicotine dependence, and PTSD symptoms partially accounted for this risk. However, marijuana dependence was only significantly related to PTSD symptoms. Clinicians and researchers should separately assess different types of dependence among trauma-exposed individuals both with and without PTSD symptoms.

Indexed as

AdultAgedAged, 80 and overAlcoholismFemaleHumansIsraelLife Change EventsMaleMarijuana AbuseMiddle AgedPrevalenceRiskStress Disorders, Post-TraumaticTobacco Use DisorderYoung Adult

Identifiers

PMID24387979
PMCPMC3965593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.