ArticleBiological psychiatry2014
Neuronal correlates of risk-seeking attitudes to anticipated losses in binge drinkers.
Article in Biological psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Common and separable neural alterations in substance use disorders: A coordinate-based meta-analyses of functional neuroimaging studies in humans.Human brain mapping · 2020Pooled it
- Subthalamic Oscillatory Activity of Reward and Loss Processing Using the Monetary Incentive Delay Task in Parkinson Disease.Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- Comparison of factor analysis models applied to the NCANDA neuropsychological test battery.PloS one · 2022Article
- Binge Drinking and Problem Gambling Association in Adolescents and Young Adults.Frontiers in human neuroscience · 2022Article
- Perceived friendship and binge drinking in young adults: A study of the Human Connectome Project data.Drug and alcohol dependence · 2021Article
- Behavioral and Cerebral Impairments Associated with Binge Drinking in Youth: A Critical Review.Psychologica Belgica · 2019Article
- The involuntary nature of binge drinking: goal directedness and awareness of intention.Addiction biology · 2018Article
- Reduced loss aversion in pathological gambling and alcohol dependence is associated with differential alterations in amygdala and prefrontal functioning.Scientific reports · 2017Article
- Electrophysiological Anomalies in Face-Name Memory Encoding in Young Binge Drinkers.Frontiers in psychiatry · 2017Article
- Overlapping Neural Endophenotypes in Addiction and Obesity.Frontiers in endocrinology · 2017Review
- The Burden of Binge and Heavy Drinking on the Brain: Effects on Adolescent and Young Adult Neural Structure and Function.Frontiers in psychology · 2017Review
- Reflection impulsivity in binge drinking: behavioural and volumetric correlates.Addiction biology · 2016Article
- Effects of outcome on the covariance between risk level and brain activity in adolescents with internet gaming disorder.NeuroImage. Clinical · 2016Article
- Conflict anticipation in alcohol dependence - A model-based fMRI study of stop signal task.NeuroImage. Clinical · 2015Article
- Exaggerated waiting impulsivity associated with human binge drinking, and high alcohol consumption in mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014Article
- Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders.Current addiction reports · 2014Review
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAbnormal decision making under risk is associated with a number of psychiatric disorders. Here, we focus on binge drinkers (BD), characterized by repeated episodes of heavy alcohol intoxication. Previous studies suggest a decreased sensitivity to aversive conditioning in BD. Here, we asked whether BD might be characterized by enhanced risk seeking related to decreased sensitivity to the anticipation of negative outcomes.
methodsUsing an anticipatory risk-taking task (40 BD and 70 healthy volunteers) and an adapted version of this task for functional magnetic resonance imaging (21 BD and 21 healthy volunteers), we assessed sensitivity to reward and loss across risk probabilities.
resultsIn the behavioral task, BD showed a higher number of risky choices in high-risk losses. In the neuroimaging task, the high-risk attitude in the loss condition was associated with greater activity in dorsolateral prefrontal, lateral orbitofrontal, and superior parietal cortices in BD. Explicit exposure of BD to the probability and magnitude of loss, via introduction of feedback, resulted in a subsequent decrease in risky choices. This change in risk attitude in BD was associated with greater activity in inferior frontal gyrus, which also correlated with the percentage of decrease in risky choices after feedback presentation, suggesting a possible role for cognitive control toward risk-seeking attitudes.
conclusionsOur findings suggest that a decrease in sensitivity to the anticipation of high-risk negative outcomes might underlie BD behavior. Presentation of explicit feedback of probability and loss in BD can potentially modify risk-taking attitudes, which have important public health implications and suggest possible therapeutic targets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.