Evidence map›Paper›PMID 24387558›Full record

ArticleChaos (Woodbury, N.Y.)2013

Shock-induced termination of reentrant cardiac arrhythmias: comparing monophasic and biphasic shock protocols.

Jean Bragard, Ana Simic, Jorge Elorza, Roman O Grigoriev, Elizabeth M Cherry, Robert F Gilmour, Niels F Otani, Flavio H Fenton

Abstract read
In one paragraph

Article in Chaos (Woodbury, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jean BragardDepartment of Physics & Applied Math., University of Navarra, Pamplona, Spain.
Ana SimicDepartment of Physics & Applied Math., University of Navarra, Pamplona, Spain.
Jorge ElorzaDepartment of Physics & Applied Math., University of Navarra, Pamplona, Spain.
Roman O GrigorievSchool of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.
Elizabeth M CherrySchool of Mathematical Sciences, Rochester Institute of Technology, Rochester, New York 14623, USA.
Robert F GilmourUniversity of Prince Edward Island, Charlottetown C1A 4P3, Canada.
Niels F OtaniSchool of Mathematical Sciences, Rochester Institute of Technology, Rochester, New York 14623, USA.
Flavio H FentonSchool of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.

Funding

Dynamical Heterogeneity of Refractoriness and the Induction of ReentryR01HL089271 · NHLBI · ROCHESTER INSTITUTE OF TECHNOLOGY · PI OTANI, NIELS F · 2009 to 2013
$2.2M
NHLBI NIH HHS R01 HL089271NHLBI NIH HHS R01HL089271
6 · The paper itself

Abstract

In this article, we compare quantitatively the efficiency of three different protocols commonly used in commercial defibrillators. These are based on monophasic and both symmetric and asymmetric biphasic shocks. A numerical one-dimensional model of cardiac tissue using the bidomain formulation is used in order to test the different protocols. In particular, we performed a total of 4.8 × 10(6) simulations by varying shock waveform, shock energy, initial conditions, and heterogeneity in internal electrical conductivity. Whenever the shock successfully removed the reentrant dynamics in the tissue, we classified the mechanism. The analysis of the numerical data shows that biphasic shocks are significantly more efficient (by about 25%) than the corresponding monophasic ones. We determine that the increase in efficiency of the biphasic shocks can be explained by the higher proportion of newly excited tissue through the mechanism of direct activation.

Indexed as

Electric CountershockModels, CardiovascularMyocardiumArrhythmias, CardiacHumans

Identifiers

PMID24387558
PMCPMC3843767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.