ArticleTropical medicine & international health : TM & IH2014
Oral lesions among HIV-infected children on antiretroviral treatment in West Africa.
Article in Tropical medicine & international health : TM & IH, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The Prevalence, Etiological Agents, Clinical Features, Treatment, and Diagnosis of HIV-Associated Oral Candidiasis in Pediatrics Across the World: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2021Pooled it
- Oral health among HIV-positive and HIV-negative children in Phnom Penh, Cambodia: a cross-sectional study.BMJ paediatrics open · 2021Trial
- Evaluation of oral lesions and dental health in HIV-positive Saudi patients.The Saudi dental journal · 2024Article
- Age-specific associations with dental caries in HIV-infected, exposed but uninfected and HIV-unexposed uninfected children in Nigeria.BMC oral health · 2022Article
- Prevalence of oral mucosal lesions in human immunodeficiency virus-infected children attending the Pediatric Infectious Diseases Clinic in Cape Town.Clinical and experimental dental research · 2022Article
- Article
- Oral Health Status of Young People Infected with HIV in High Epidemic Area of China.Journal of multidisciplinary healthcare · 2021Article
- Dental caries status of children receiving Highly active antiretroviral therapy (HAART) - A multicentric cross-sectional study in Tamil Nadu, India.Journal of family medicine and primary care · 2020Article
- Caries experience and oral health related quality of life in a cohort of Ugandan HIV-1 exposed uninfected children compared with a matched cohort of HIV unexposed uninfected children.BMC public health · 2020Article
- Oral status of HIV-infected children aged 12 years or younger who attended a Paediatric Infectious Diseases Clinic in Cape Town.Clinical and experimental dental research · 2020Article
- Oral Manifestations in HIV-Positive Children: A Systematic Review.Pathogens (Basel, Switzerland) · 2020Review
- Tooth wear in patients treated with HIV anti-retroviral therapy.BMC oral health · 2019Article
- The burden of oral conditions among adolescents living with HIV at a clinic in Johannesburg, South Africa.PloS one · 2019Article
- The association between oral disease and type of antiretroviral therapy among perinatally HIV-infected youth.AIDS (London, England) · 2018Article
- Emerging and changing viral diseases in the new millennium.Oral diseases · 2016Review
- The Burden of Oral Disease among Perinatally HIV-Infected and HIV-Exposed Uninfected Youth.PloS one · 2016Article
- Oral health status and its impact on the quality of life of children and adolescents living with HIV-1.BMC research notes · 2014Article
Corrections and comments
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Authors and funding
15 authors at 9 institutions in 4 countries.
Funding
Abstract
objectiveTo estimate the prevalence of oral mucosal diseases and dental caries among HIV-infected children receiving antiretroviral treatment (ART) in West Africa and to identify the factors associated with the prevalence of oral mucosal lesions.
methodsMulticentre cross-sectional survey in five paediatric HIV clinics in Côte d'Ivoire, Mali and Sénégal. A standardised examination was performed by trained dentists on a random sample of HIV-infected children aged 5-15 years receiving ART. The prevalence of oral and dental lesions and mean number of decayed, missing/extracted and filled teeth (DMFdefT) in temporary and permanent dentition were estimated with their 95% confidence interval (95% CI). We used logistic regression to explore the association between children's characteristics and the prevalence of oral mucosal lesions, expressed as prevalence odds ratio (POR).
resultsThe median age of the 420 children (47% females) enrolled was 10.4 years [interquartile range (IQR) = 8.3-12.6]. The median duration on ART was 4.6 years (IQR = 2.6-6.2); 84 (20.0%) had CD4 count<350 cells/mm(3). A total of 35 children (8.3%; 95% CI: 6.1-11.1) exhibited 42 oral mucosal lesions (24 were candidiasis); 86.0% (95% CI = 82.6-89.3) of children had DMFdefT ≥ 1. The presence of oral mucosal lesions was independently associated with CD4 count < 350 cells/mm(3) (POR = 2.96, 95% CI = 1.06-4.36) and poor oral hygiene (POR = 2.69, 95% CI = 1.07-6.76).
conclusionsOral mucosal lesions still occur in HIV-infected African children despite ART, but rarely. However, dental caries were common and severe in this population, reflecting the need to include oral health in the comprehensive care of HIV.
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