ArticlePloS one2013
Neuromagnetic abnormality of motor cortical activation and phases of headache attacks in childhood migraine.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00600717 (Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetoencephalography studies in migraine and headache disorders: A systematic review.Headache · 2025Pooled it
- Detecting Event-Related Spectral Perturbations in Right-Handed Sensorimotor Cortical Responses Using OPM-MEG.Bioengineering (Basel, Switzerland) · 2025Article
- Silica nanoparticles enhance the cyto- and hemocompatibility of a multilayered extracellular matrix scaffold for vascular tissue regeneration.Biotechnology letters · 2024Article
- Improved Biomagnetic Signal-To-Noise Ratio and Source Localization Using Optically Pumped Magnetometers with Synthetic Gradiometers.Brain sciences · 2023Article
- Spatial and Frequency Specific Artifact Reduction in Optically Pumped Magnetometer Recordings.Journal of integrative neuroscience · 2022Article
- Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study.Frontiers in psychiatry · 2021Article
- Abnormality of visual neuromagnetic activation in female migraineurs without aura between attacks.The journal of headache and pain · 2019Article
- Investigating Brain MRI Findings in Children with Headache.Iranian journal of child neurology · 2018Article
- Spatial Heterogeneity of Cortical Excitability in Migraine Revealed by Multifrequency Neuromagnetic Signals.The journal of pain · 2016Article
- Quantitative neuromagnetic signatures of aberrant cortical excitability in pediatric chronic migraine.The journal of headache and pain · 2016Article
- Multi-frequency analysis of brain connectivity networks in migraineurs: a magnetoencephalography study.The journal of headache and pain · 2016Article
- Resting state brain activity in patients with migraine: a magnetoencephalography study.The journal of headache and pain · 2015Article
- Gamma deficits as a neural signature of cognitive impairment in children treated for brain tumors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The cerebral cortex serves a primary role in the pathogenesis of migraine. This aberrant brain activation in migraine can be noninvasively detected with magnetoencephalography (MEG). The objective of this study was to investigate the differences in motor cortical activation between attacks (ictal) and pain free intervals (interictal) in children and adolescents with migraine using both low- and high-frequency neuromagnetic signals. Thirty subjects with an acute migraine and 30 subjects with a history of migraine, while pain free, were compared to age- and gender-matched controls using MEG. Motor cortical activation was elicited by a standardized, validated finger-tapping task. Low-frequency brain activation (1~50 Hz) was analyzed with waveform measurements and high-frequency oscillations (65-150 Hz) were analyzed with wavelet-based beamforming. MEG waveforms showed that the ictal latency of low-frequency brain activation was significantly delayed as compared with controls, while the interictal latency of brain activation was similar to that of controls. The ictal amplitude of low-frequency brain activation was significantly increased as compared with controls, while the interictal amplitude of brain activation was similar to that of controls. The ictal source power of high-frequency oscillations was significantly stronger than that of the controls, while the interictal source power of high-frequency oscillations was significantly weaker than that of controls. The results suggest that aberrant low-frequency brain activation in migraine during a headache attack returned to normal interictally. However, high-frequency oscillations changed from ictal hyper-activation to interictal hypo-activation. Noninvasive assessment of cortical abnormality in migraine with MEG opens a new window for developing novel therapeutic strategies for childhood migraine by maintaining a balanced cortical excitability.
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