ArticleGenetics and molecular biology2013
Downregulation of caffeoyl-CoA O-methyltransferase (CCoAOMT) by RNA interference leads to reduced lignin production in maize straw.
Article in Genetics and molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 94 citations in OpenAlex.
- Genome-Wide Identification of the Caffeoyl Coenzyme A 3-O-Methyltransferase Family Genes and Their Role in the Lodging Resistance of Wheat (Plants (Basel, Switzerland) · 2026Article
- MsCCoAOMTh3 confers drought tolerance by mediating lignin content and ROS scavenging.Plant molecular biology · 2026Article
- Genome-wide identification and expression analysis ofFrontiers in plant science · 2025Article
- Genome-Wide Analysis of Caffeoyl-CoA-O-methyltransferase (CCoAOMT) Family Genes and the Roles ofPlants (Basel, Switzerland) · 2024Article
- Engineered reduction of S-adenosylmethionine alters lignin in sorghum.Biotechnology for biofuels and bioproducts · 2024Article
- Breeding for improved digestibility and processing of lignocellulosic biomass inFrontiers in plant science · 2024Review
- Development of an in vitro regeneration system from immature inflorescences and CRISPR/Cas9-mediated gene editing in sudangrass.Journal, genetic engineering & biotechnology · 2023Article
- Microscopic and metabolic investigations disclose the factors that lead to skin cracking in chili-type pepper fruit varieties.Horticulture research · 2023Article
- Overexpression of Bacterial Beta-Ketothiolase Improves Flax (Metabolites · 2023Article
- Modulation of lignin biosynthesis for drought tolerance in plants.Frontiers in plant science · 2023Review
- Genome Identification and Expression Profiles in Response to Nitrogen Treatment Analysis of the Class I CCoAOMT Gene Family in Populus.Biochemical genetics · 2022Article
- Overexpression ofFrontiers in plant science · 2022Article
- The Genetic Architecture of Nitrogen Use Efficiency in Switchgrass (Frontiers in plant science · 2022Article
- Transcriptome Analyses of Barley Roots Inoculated with NovelPlants (Basel, Switzerland) · 2021Article
- Association of gene expression with syringyl to guaiacyl ratio in sugarcane lignin.Plant molecular biology · 2021Article
- Tartary Buckwheat (International journal of molecular sciences · 2021Article
- Genome-wide analysis of general phenylpropanoid and monolignol-specific metabolism genes in sugarcane.Functional & integrative genomics · 2021Article
- The caffeoyl-CoA O-methyltransferase gene SNP replacement in Russet Burbank potato variety enhances late blight resistance through cell wall reinforcement.Plant cell reports · 2021Article
- Phylogenetic Occurrence of the Phenylpropanoid Pathway and Lignin Biosynthesis in Plants.Frontiers in plant science · 2021Review
- Overexpression ofFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignin is a major cell wall component of vascular plants that provides mechanical strength and hydrophobicity to vascular vessels. However, the presence of lignin limits the effective use of crop straw in many agroindustrial processes. Here, we generated transgenic maize plants in which the expression of a lignin biosynthetic gene encoding CCoAOMT, a key enzyme involved in the lignin biosynthesis pathway was downregulated by RNA interference (RNAi). RNAi of CCoAOMT led to significantly downregulated expression of this gene in transgenic maize compared with WT plants. These transgenic plants exhibited a 22.4% decrease in Klason lignin content and a 23.3% increase in cellulose content compared with WT plants, which may reflect compensatory regulation of lignin and cellulose deposition. We also measured the lignin monomer composition of the RNAi plants by GC-MS and determined that transgenic plants had a 57.08% higher S/G ratio than WT plants. In addition, histological staining of lignin with Wiesner reagent produced slightly more coloration in the xylem and sclerenchyma than WT plants. These results provide a foundation for breeding maize with low-lignin content and reveal novel insights about lignin regulation via genetic manipulation of CCoAOMT expression.
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