Evidence map›Paper›PMID 24385599›Full record

ArticleGut2014

Source of dietary fibre and diverticular disease incidence: a prospective study of UK women.

Francesca L Crowe, Angela Balkwill, Benjamin J Cairns, Paul N Appleby, Jane Green, Gillian K Reeves, Timothy J Key, Valerie Beral, Million Women Study Collaborators, Million Women Study Collaborators

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 6 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 6 syntheses or guidelines pooled it, 132 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Francesca L CroweCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Angela BalkwillCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Benjamin J CairnsCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Paul N ApplebyCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Jane GreenCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Gillian K ReevesCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Timothy J KeyCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Valerie BeralCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Million Women Study Collaborators
Million Women Study Collaborators
University of Oxford · GB

Funding

Cancer Research UK 16491Cancer Research UK C570/A11692Medical Research Council G0700474Medical Research Council MR/K02700X/1
6 · The paper itself

Abstract

backgroundPrevious prospective studies have found the incidence of intestinal diverticular disease decreased with increasing intakes of dietary fibre, but associations by the fibre source are less well characterised. We assessed these associations in a large UK prospective study of middle-aged women. METHODS AND

findingsDuring 6 (SD 1) years follow-up of 690 075 women without known diverticular disease who had not changed their diet in the last 5 years, 17 325 were admitted to hospital or died with diverticular disease. Dietary fibre intake was assessed using a validated 40-item food questionnaire and remeasured 1 year later in 4265 randomly-selected women. Mean total dietary fibre intake at baseline was 13.8 (SD 5.0) g/day, of which 42% came from cereals, 22% from fruits, 19% from vegetables (not potatoes) and 15% from potatoes. The relative risk (95% CI) for diverticular disease per 5 g/day fibre intake was 0.86 (0.84 to 0.88). There was significant heterogeneity by the four main sources of fibre (p<0.0001), with relative risks, adjusted for each of the other sources of dietary fibre of 0.84 (0.81 to 0.88) per 5 g/day for cereal, 0.81 (0.77 to 0.86) per 5 g/day for fruit, 1.03 (0.93 to 1.14) per 5 g/day for vegetable and 1.04 (1.02 to 1.07) per 1 g/day for potato fibre.

conclusionsA higher intake of dietary fibre is associated with a reduced risk of diverticular disease. The associations with diverticular disease appear to vary by fibre source, and the reasons for this variation are unclear.

Indexed as

Dietary FiberAgedDiet SurveysDiverticulitisDiverticulumFemaleFollow-Up StudiesHumansIncidenceIntestinal DiseasesMiddle AgedProspective StudiesRiskSurveys and QuestionnairesUnited KingdomDietary Fiberdietdietary fibrediverticular diseaseprospective

Identifiers

PMID24385599
PMCPMC4145436
OpenAlexW2122462294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.