Evidence map›Paper›PMID 24382326›Full record

ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2014

Epidemiology of viral respiratory infections in a tertiary care centre in the era of molecular diagnosis, Geneva, Switzerland, 2011-2012.

J Ambrosioni, P-O Bridevaux, G Wagner, A Mamin, L Kaiser

Registry-linked trialAbstract read
In one paragraph

Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03224026 (Which Virus Leads to Viremia in Children With Fever Without Source and do New Biomarkers Correlate With Viral and Bacterial Infections?), which is not on this map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03224026 completednot on this mapstarted 2015, after this paper: background citation

Which Virus Leads to Viremia in Children With Fever Without Source and do New Biomarkers Correlate With Viral and Bacterial Infections?

TypeobservationalSponsorMeMed Diagnostics Ltd.Ran2015 to 2018Enrolled206ConditionsInfectious Disease, Fever, Viremia
3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Trial
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  3. Vitamin D Supplementation and the Risk of Colds in Patients with Asthma.American journal of respiratory and critical care medicine · 2016
    Trial
  4. Trial
  5. Article
  6. A rapid surveillance of pneumonia in hospitalized patients: an opportunity for intervention.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Article
  7. Article
  8. Article
  9. Interplay between respiratory viruses and cilia in the airways.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  10. Article
  11. Article
  12. Article
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  14. Review
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J AmbrosioniLaboratory of Virology, Division of Laboratory Medicine, University of Geneva Hospitals, Geneva, Switzerland; Division of Infectious Diseases, University of Geneva Hospitals, Geneva, Switzerland.
P-O Bridevaux
G Wagner
A Mamin
L Kaiser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies have examined the epidemiology of respiratory viral infections in large tertiary centres over more than one season in the era of molecular diagnosis. Respiratory clinical specimens received between 1 January 2011 and 31 December 2012 were analysed. Respiratory virus testing was performed using a large panel of real-time PCR or RT-PCR. Results were analysed according to sample type (upper versus lower respiratory tract) and age group. In all, 2996 (2469 (82.4%) upper; 527 (17.6%) lower) specimens were analysed. Overall positivity rate was 47.4% and 23.7% for upper and lower respiratory samples, respectively. The highest positivity rate was observed in patients under 18 years old (p <0.001); picornaviruses were the most frequent viruses detected over the year. Influenza virus, respiratory syncytial virus, human metapneumovirus and coronaviruses showed a seasonal peak during the winter season, while picornaviruses and adenoviruses were less frequently detected in these periods. Multiple viral infections were identified in 12% of positive cases and were significantly more frequent in children (p <0.001). In conclusion, we observed significant differences in viral infection rates and virus types among age groups, clinical sample types and seasons. Follow-up of viral detection over several seasons allows a better understanding of respiratory viral epidemiology.

Indexed as

Molecular Diagnostic TechniquesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCoinfectionFemaleHumansInfantInfant, NewbornMaleMiddle AgedPrevalenceReal-Time Polymerase Chain ReactionAdenoviruscoronavirusepidemiologyinfluenzapicornavirusrespiratory syncytial virusrespiratory virusseasonality

Identifiers

PMID24382326
PMCPMC7128668

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.