Evidence map›Paper›PMID 24382133›Full record

ArticleAIDS care2014

Risk factors for recent nonfatal overdose among HIV-infected Russians who inject drugs.

Alexander Y Walley, Debbie M Cheng, Sharon M Coleman, Evgeny Krupitsky, Anita Raj, Elena Blokhina, Carly Bridden, Christine E Chaisson, Marlene C Lira, Jeffrey H Samet

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Alexander Y Walleya Clinical Addiction Research and Education Unit, Section of General Internal Medicine , Boston University School of Medicine, Boston Medical Center , Boston , MA , USA.
Debbie M Cheng
Sharon M Coleman
Evgeny Krupitsky
Anita Raj
Elena Blokhina
Carly Bridden
Christine E Chaisson
Marlene C Lira
Jeffrey H Samet
Boston University · USBoston Medical Center · USFirst Pavlov State Medical University of St. Petersburg · RUInstitute of the Americas · USSt.Petersburg V.M.Bekhterev Psychoneurological Research Institute · RU

Funding

Neuropathology CoreP30AG013846 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KOWALL, NEIL W. · 1996 to 2020
$29.1M
URBAN ARCH (2/5) Biostatistics and Data Management Core (BDM)U24AA020779 · NIAAA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHENG, DEBBIE M. · 2011 to 2020
$3.6M
URBAN ARCH (1/5) Administrative Coordinating Core (Admin Core)U24AA020778 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2011 to 2020
$3.5M
Maximizing Opportunity - HIV Prevention in Hospitalized Russian DrinkersR01AA016059 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2006 to 2010
$3.2M
Impact of Alcohol Use on HIV Infection--In the United States and RussiaK24AA015674 · NIAAA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2006 to 2010
$756k
NIAAA NIH HHS K24 AA015674NIAAA NIH HHS K24AA015674NIAAA NIH HHS R01 AA016059NIAAA NIH HHS R01-AA016059NIAAA NIH HHS U24 AA020778NIAAA NIH HHS U24AA020778NIAAA NIH HHS U24 AA020779NIAAA NIH HHS U24AA020779NIA NIH HHS P30 AG013846
6 · The paper itself

Abstract

Overdoses and HIV infection are common among Russians who inject drugs, yet risk factors have not been studied. We analyzed baseline data of 294 participants with 30-day injection drug use from an HIV secondary prevention trial for persons reporting "heavy" alcohol use (National Institute on Alcohol Abuse and Alcoholism [NIAAA] risky drinking definition) and risky sex in the past 6 months. The outcome was any self-reported overdose in the previous 3 months. We examined demographic, HIV-related, criminal justice, mental health, substance use, and injection risk factors. Participants' characteristics included median age 29 years, 117/294 (40%) female, and median CD4 cell count 345/µl. Over three quarters 223/294 (76%) reported a history of overdose and 47/294 (16%) reported overdose in the past 3 months. Past month injection frequency (adjusted odds ratio [AOR] 4.77, 95% confidence interval [CI]: 1.63-14.0 highest vs. lowest quartile; AOR 3.58, 95% CI: 1.20-10.69 second highest vs. lowest quartile) and anti-retroviral therapy (ART) at time of interview (AOR 3.96 95% CI: 1.33-11.83) were associated with 3-month overdose. Nonfatal overdose among HIV-infected Russians who inject drugs is common. Risk factors include injection frequency and anti-retroviral therapy (ART), which warrant further study. Overdose prevention efforts are needed among HIV-infected Russians who inject drugs.

Indexed as

Risk-TakingAdultAlcoholismAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountConfidence IntervalsCross-Sectional StudiesDrug OverdoseFemaleHIV InfectionsHumansMaleOdds RatioRisk FactorsRussiaSelf Disclosureanti-retroviral therapyHIVinjection drug useoverdoseRussia

Identifiers

PMID24382133
PMCPMC4040021
OpenAlexW2002774686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.