ArticleJAMA2014
Glucocorticoids for acute viral bronchiolitis in infants and young children.
Article in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Working group summary of the 2023 full update of the Finnish national guidelines for paediatric lower respiratory tract infections.Acta paediatrica (Oslo, Norway : 1992) · 2025Guideline
- Respiratory and Gut Microbiome Modification during Respiratory Syncytial Virus Infection: A Systematic Review.Viruses · 2024Pooled it
- Normal saline for children with bronchiolitis: study protocol for a randomised controlled non-inferiority trial.BMJ paediatrics open · 2024Article
- Article
- Efficacy of 3% hypertonic saline in bronchiolitis: A meta-analysis.Experimental and therapeutic medicine · 2019Article
- Viral Aetiology of Bronchiolitis in Hospitalised Children in a Tertiary Center in Tehran.Maedica · 2018Article
- Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals.Acta paediatrica (Oslo, Norway : 1992) · 2017Article
- [Effect of atopy on serum glucocorticoid receptor levels in children with bronchiolitis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- A Systematic Review and Comprehensive Critical Analysis Examining the Use of Prednisolone for the Treatment of Mild to Moderate Croup.The open nursing journal · 2017Article
- Improvement of the Prediction of Drugs Demand Using Spatial Data Mining Tools.Journal of medical systems · 2016Article
- Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials.Influenza and other respiratory viruses · 2015Review
- Impact of a Bronchiolitis Clinical Pathway on Management Decisions by Preferred Language.Pediatric quality & safetyArticle
Corrections and comments
- Comment on
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
clinical questionAre glucocorticoids, alone or combined with bronchodilators, associated with reduced admission rates, length of stay, or improvements in clinical severity scores without increased adverse effects in infants and young children with acute viral bronchiolitis? BOTTOM LINE: There is no consistent clinically relevant association of single therapy with systemic or inhaled glucocorticoids and improved outcomes in either outpatient or inpatient settings. Exploratory evidence suggests that combined glucocorticoids and nebulized epinephrine may be associated with lower hospitalization rates in outpatients, but these findings must be interpreted cautiously.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.