Evidence map›Paper›PMID 24381556›Full record

ArticleFrontiers in neuroinformatics2013

High-throughput neuro-imaging informatics.

Michael I Miller, Andreia V Faria, Kenichi Oishi, Susumu Mori

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Baby brain atlases.NeuroImage · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. NeuroImage. Clinical · 2018
    Article
  12. Article
  13. DTI Analysis of Presbycusis Using Voxel-Based Analysis.AJNR. American journal of neuroradiology · 2016
    Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael I MillerCenter for Imaging Science, Johns Hopkins Whiting School of Engineering, The Johns Hopkins University Baltimore, MD, USA ; Institute for Computational Medicine, Johns Hopkins School of Medicine and Whiting School of Engineering, The Johns Hopkins University Baltimore, MD, USA ; Department of Biomedical Engineering, The Johns Hopkins University Baltimore, MD, USA.
Andreia V FariaThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine Baltimore, MD, USA.
Kenichi OishiThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine Baltimore, MD, USA.
Susumu MoriThe Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine Baltimore, MD, USA.

Funding

The CardioVascular Research GridR24HL085343 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2007 to 2015
$19.4M
X-LINKED ADRENOLEUKODYSTROPHYP41RR015241 · NCRR · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MC DONALD, JOHN · 2001 to 2011
$18.5M
TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2012 to 2020
$13.1M
Biomarkers of Cognitive Decline among Normal Individuals: The BIOCARD cohortU01AG033655 · NIA · JOHNS HOPKINS UNIVERSITY · PI ALBERT, MARILYN S. · 2009 to 2013
$11.2M
STRUCTURE, FUNCTION AND COGNITION IN SCHIZOPHRENIAP50MH071616 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA · 2004 to 2008
$11.2M
Simulation Tools for Dynamic CTR01EB001838 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SAMEI, EHSAN, SEGARS, WILLIAM P · 2005 to 2023
$6.9M
NEUROMORPHOMETRY IN SCHIZOPHRENIA BY COMPUTER ALGORITHMR01MH056584 · NIMH · WASHINGTON UNIVERSITY · PI CSERNANSKY, JOHN G · 1998 to 2011
$4.2M
Continued Development and Maintenance of MriStudioR01NS084957 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MILLER, MICHAEL I, MORI, SUSUMU · 2013 to 2022
$3.6M
Validation of Structural/Functional MRI LocalizationR01EB000975 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BARTA, PATRICK E, MILLER, MICHAEL I · 2002 to 2012
$3.0M
Development of quantitative MRI DTI analysis tool for preterm neonateR01HD065955 · NICHD · JOHNS HOPKINS UNIVERSITY · PI OISHI, KENICHI · 2011 to 2015
$2.3M
Large-Scale Compute Cluster for the Institute for Computational MedicineS10RR025053 · NCRR · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2008 to 2008
$2.0M
3D Shape Analysis for Computational AnatomyR01EB008171 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI MILLER, MICHAEL I · 2009 to 2012
$2.0M
NCRR NIH HHS P41 RR015241NCRR NIH HHS S10 RR025053NHLBI NIH HHS R24 HL085343NIA NIH HHS R21 AG033774NIA NIH HHS U01 AG033655NIBIB NIH HHS P41 EB015909NIBIB NIH HHS R01 EB000975NIBIB NIH HHS R01 EB001838NIBIB NIH HHS R01 EB008171NIBIB NIH HHS R01 EB017638NICHD NIH HHS R01 HD065955NIMH NIH HHS P50 MH071616NIMH NIH HHS R01 MH056584NIMH NIH HHS R01 MH084803NINDS NIH HHS R01 NS084957NINDS NIH HHS U01 NS082085
6 · The paper itself

Abstract

This paper describes neuroinformatics technologies at 1 mm anatomical scale based on high-throughput 3D functional and structural imaging technologies of the human brain. The core is an abstract pipeline for converting functional and structural imagery into their high-dimensional neuroinformatic representation index containing O(1000-10,000) discriminating dimensions. The pipeline is based on advanced image analysis coupled to digital knowledge representations in the form of dense atlases of the human brain at gross anatomical scale. We demonstrate the integration of these high-dimensional representations with machine learning methods, which have become the mainstay of other fields of science including genomics as well as social networks. Such high-throughput facilities have the potential to alter the way medical images are stored and utilized in radiological workflows. The neuroinformatics pipeline is used to examine cross-sectional and personalized analyses of neuropsychiatric illnesses in clinical applications as well as longitudinal studies. We demonstrate the use of high-throughput machine learning methods for supporting (i) cross-sectional image analysis to evaluate the health status of individual subjects with respect to the population data, (ii) integration of image and personal medical record non-image information for diagnosis and prognosis.

Indexed as

computational anatomyfunctional imagingneuro-imagingneuroinformatics

Identifiers

PMID24381556
PMCPMC3865387

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.