ArticlePhysiology and molecular biology of plants : an international journal of functional plant biology2013
Improved silymarin content in elicited multiple shoot cultures of Silybum marianum L.
Article in Physiology and molecular biology of plants : an international journal of functional plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 32 citations in OpenAlex.
- GGV formula attenuates CClFrontiers in nutrition · 2025Article
- Adsorption of Basic Yellow 28 and Basic Blue 3 Dyes from Aqueous Solution Using Silybum Marianum Stem as a Low-Cost Adsorbent.Molecules (Basel, Switzerland) · 2023Article
- Evaluation of the effects ofSaudi journal of biological sciences · 2021Article
- Salicylic acid increases flavonolignans accumulation in the fruits of hydroponically culturedSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Review
- Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations.Fitoterapia · 2017Article
- Enhancement of silymarin and phenolic compound accumulation in tissue culture of Milk thistle using elicitor feeding and hairy root cultures.Journal, genetic engineering & biotechnology · 2016Article
- Evaluation of biochemical markers during somatic embryogenesis in Silybum marianum L.3 Biotech · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silybum marianum L. extracts are being used as antihepatotoxic therapy for liver diseases. Silymarin is a polyphenolic flavonoid mixture isolated from milk thistle which is believed to be responsible for the plant's hepatoprotective action. Regeneration of Silybum marianum plants from shoot tip explants and assessment of their morphogenic potential, silymarin total concentration and its major constituents upon exposure to medium composition alteration and different elicitors' application was targeted. Different concentrations of NaCl, quercetin, gamma irradiation and dried fungal extracts were used to elicit silymarin production in the cultures. The chemical composition of silymarin and its total concentration was investigated through HPLC at all the experiment stages. Multiple shoots were recorded after 3 weeks of culture on MS medium containing various concentrations of BA and/or NAA. IAA was more effective than NAA and IBA in inducing robust roots in shoot cultures. The flowering plants recorded 20 % and 40 % of the total plants number in the multiplication and rooting stages respectively. The highest total silymarin concentration reached its peak with (10 Gy) gamma-irradiation to be 6.598 % dry weight in the in vitro regenerated shoot tip explants. The in vitro grown flowers showed 1.7 times more sylimarin productivity as compared to that of the wild grown congruent.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.