Evidence map›Paper›PMID 24381442›Full record

ArticlePhysiology and molecular biology of plants : an international journal of functional plant biology2013

Micropropagation and non-steroidal anti-inflammatory and anti-arthritic agent boswellic acid production in callus cultures of Boswellia serrata Roxb.

Tukaram D Nikam, Ravi P Ghorpade, Kirti M Nitnaware, Mahendra L Ahire, Vinayak H Lokhande, Arvind Chopra

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Article in Physiology and molecular biology of plants : an international journal of functional plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Phytochemical Profiles and Cytotoxic Activity ofPlants (Basel, Switzerland) · 2024
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tukaram D NikamDepartment of Botany, University of Pune, Pune, 411 007 India.
Ravi P GhorpadeDepartment of Botany, University of Pune, Pune, 411 007 India ; Centre for Rheumatic Diseases, 11, Hermes Elegance, 1988 Convent Street, Camp, Pune, 411 001 India.
Kirti M NitnawareDepartment of Botany, University of Pune, Pune, 411 007 India.
Mahendra L AhireDepartment of Botany, University of Pune, Pune, 411 007 India.
Vinayak H LokhandeDepartment of Botany, University of Pune, Pune, 411 007 India.
Arvind ChopraCentre for Rheumatic Diseases, 11, Hermes Elegance, 1988 Convent Street, Camp, Pune, 411 001 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micropropagation through cotyledonary and leaf node and boswellic acid production in stem callus of a woody medicinal endangered tree species Boswellia serrata Roxb. is reported. The response for shoots, roots and callus formation were varied in cotyledonary and leafy nodal explants from in vitro germinated seeds, if inoculated on Murshige and Skoog's (MS) medium fortified with cytokinins and auxins alone or together. A maximum of 8.0 ± 0.1 shoots/cotyledonary node explant and 6.9 ± 0.1 shoots/leafy node explants were produced in 91 and 88 % cultures respectively on medium with 2.5 μM 6-benzyladenine (BA) and 200 mg l(-1) polyvinylpyrrolidone (PVP). Shoots treated with 2.5 μM IBA showed the highest average root number (4.5) and the highest percentage of rooting (89 %). Well rooted plantlets were acclimatized and 76.5 % of the plantlets showed survival upon transfer to field conditions. Randomly amplified polymorphic DNA (RAPD) analysis of the micropropagated plants compared with mother plant revealed true-to-type nature. The four major boswellic acid components in calluses raised from root, stem, cotyledon and leaf explants were analyzed using HPLC. The total content of four boswellic acid components was higher in stem callus obtained on MS with 15.0 μM IAA, 5.0 μM BA and 200 mg l(-1) PVP. The protocol reported can be used for conservation and exploitation of in vitro production of medicinally important non-steroidal anti-inflammatory metabolites of B. serrata.

Indexed as

Anti-arthriticAnti-inflammatoryBoswellia serrataBoswellic acidBurseraceaeCallusIndian olibanumMicropropagationSalai guggulSteroids

Identifiers

PMID24381442
PMCPMC3550693

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.