Evidence map›Paper›PMID 24381150›Full record

SynthesisSeminars in thrombosis and hemostasis2014

ABO blood group and vascular disease: an update.

Francesco Dentali, Anna Paola Sironi, Walter Ageno, Silvia Crestani, Massimo Franchini

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Seminars in thrombosis and hemostasis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Pulmonary Embolism and ABO Blood Type: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025
    Review
  8. Differential expression ofJournal of Taibah University Medical Sciences · 2024
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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  16. Article
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  19. ABO blood groups do not predict progression of traumatic intracranial hemorrhage.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Francesco DentaliDepartment of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
Anna Paola SironiDepartment of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
Walter AgenoDepartment of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.
Silvia CrestaniDepartment of Transfusion Medicine and Hematology, "C. Poma" Hospital, Mantova, Italy.
Massimo FranchiniDepartment of Transfusion Medicine and Hematology, "C. Poma" Hospital, Mantova, Italy.
University of Insubria · ITAzienda Ospedaliera Carlo Poma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been well known for many years that the ABO blood group has a major influence on hemostasis, through its influence on von Willebrand factor and, consequently, factor VIII plasma levels. Although the relationship between non-O blood type and the risk of venous thromboembolism is nowadays also well established, the association with arterial thrombotic events (i.e., myocardial infarction [MI] and ischemic stroke) is less well characterized. To elucidate the latter issue, we have conducted a systematic review and meta-analysis of the existing literature. After an electronic search strategy using MEDLINE and EMBASE and a manual review of abstract books of the International Society on Thrombosis and Haemostasis and of reference lists of all retrieved articles, 28 studies were finally included in our systematic review. The prevalence of non-O blood group was significantly higher in patients with MI (pooled odds ratio [OR]: 1.28, 95% confidence interval [CI]: 1.17-1.40; p < 0.001) and ischemic stroke (pooled OR: 1.17, 95% CI: 1.01-1.35; p = 0.03) than in controls. The restriction of the analysis to high quality studies only confirmed the association with MI (pooled OR: 1.17, 95% CI: 1.03-1.32) but not with ischemic stroke (pooled OR: 1.28, 95% CI: 0.94-1.74). In conclusion, the results of our meta-analysis confirm the existing literature evidence of a weak association between non-O blood group and vascular arterial thrombosis, in particular myocardial ischemia.

Indexed as

ABO Blood-Group SystemBrain IschemiaMyocardial InfarctionStrokeThrombosisFemaleHumansMalePrevalenceABO Blood-Group System

Identifiers

PMID24381150
OpenAlexW2091917386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.