Evidence map›Paper›PMID 24381034›Full record

ReviewViruses2013

Flavivirus entry receptors: an update.

Manuel Perera-Lecoin, Laurent Meertens, Xavier Carnec, Ali Amara

Abstract readReview
In one paragraph

Review in Viruses, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed.

  1. Combination of Melittin andInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Role of Cellular Mechanisms in Dengue Pathogenesis: Focus on Immune Cells Interactions.Combinatorial chemistry & high throughput screening · 2026
    Review
  8. Article
  9. Article
  10. LRP8 is an entry receptor for tick-borne encephalitis viruses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manuel Perera-LecoinINSERM U944, CNRS 7212, Laboratoire de Pathologie et Virologie Moléculaire, Hôpital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France. manuel.perera@inserm.fr.
Laurent MeertensINSERM U944, CNRS 7212, Laboratoire de Pathologie et Virologie Moléculaire, Hôpital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France. laurent.meertens@inserm.fr.
Xavier CarnecINSERM U944, CNRS 7212, Laboratoire de Pathologie et Virologie Moléculaire, Hôpital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France. xavier.carnec@gmail.com.
Ali AmaraINSERM U944, CNRS 7212, Laboratoire de Pathologie et Virologie Moléculaire, Hôpital Saint-Louis, 1 Avenue Claude Vellefaux, Paris 75010, France. ali.amara@inserm.fr.

Funding

TAM Receptors and Virus InfectionR01AI101400 · NIAID · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI DIAMOND, MICHAEL S, KLEIN, ROBYN S. · 2012 to 2021
$5.8M
NIAID NIH HHS AI101400NIAID NIH HHS R01 AI101400
6 · The paper itself

Abstract

Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with cell surface receptors. The current model suggests that flaviviruses use at least two different sets of molecules for infectious entry: attachment factors that concentrate and/or recruit viruses on the cell surface and primary receptor(s) that bind to virions and direct them to the endocytic pathway. Here, we present the currently available knowledge regarding the flavivirus receptors described so far with specific attention to C-type lectin receptors and the phosphatidylserine receptors, T-cell immunoglobulin and mucin domain (TIM) and TYRO3, AXL and MER (TAM). Their role in flavivirus attachment and entry as well as their implication in the virus biology will be discussed in depth.

Indexed as

Virus InternalizationAnimalsEndocytosisFlavivirusHumansLectins, C-TypeReceptors, Cell SurfaceReceptors, VirusVirus AttachmentLectins, C-Typephosphatidylserine receptorReceptors, Cell SurfaceReceptors, Virus

Identifiers

PMID24381034
PMCPMC3917432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.