ArticleJournal of neurophysiology2014
Taste coding in the parabrachial nucleus of the pons in awake, freely licking rats and comparison with the nucleus of the solitary tract.
Article in Journal of neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures.Current neuropharmacology · 2024Review
- Neural Coding of Food Is a Multisensory, Sensorimotor Function.Nutrients · 2021Review
- Enhancing GABAergic Tone in the Rostral Nucleus of the Solitary Tract Reconfigures Sensorimotor Neural Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Article
- Layer- and Cell Type-Specific Response Properties of Gustatory Cortex Neurons in Awake Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Dynamic Representation of Taste-Related Decisions in the Gustatory Insular Cortex of Mice.Current biology : CB · 2020Article
- Cortical processing of chemosensory and hedonic features of taste in active licking mice.Journal of neurophysiology · 2020Article
- Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.Chemical senses · 2019Review
- Heterogeneity of neuronal responses in the nucleus of the solitary tract suggests sensorimotor integration in the neural code for taste.Journal of neurophysiology · 2019Article
- Taste Responses in the Nucleus of the Solitary Tract of Awake Obese Rats Are Blunted Compared With Those in Lean Rats.Frontiers in integrative neuroscience · 2019Article
- Central taste anatomy and physiology.Handbook of clinical neurology · 2019Review
- Taste coding of complex naturalistic taste stimuli and traditional taste stimuli in the parabrachial pons of the awake, freely licking rat.Journal of neurophysiology · 2016Article
- Dynamic taste responses of parabrachial pontine neurons in awake rats.Journal of neurophysiology · 2016Article
- Topographic organizations of taste-responsive neurons in the parabrachial nucleus of C57BL/6J mice: An electrophysiological mapping study.Neuroscience · 2016Article
- Spontaneous Changes in Taste Sensitivity of Single Units Recorded over Consecutive Days in the Brainstem of the Awake Rat.PloS one · 2016Article
- State Dependency of Chemosensory Coding in the Gustatory Thalamus (VPMpc) of Alert Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Odor-taste convergence in the nucleus of the solitary tract of the awake freely licking rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Somatostatin and corticotrophin releasing hormone cell types are a major source of descending input from the forebrain to the parabrachial nucleus in mice.Chemical senses · 2014Article
- Stimulation of spinal afferents from skin activates parabrachial neurons that respond to taste.Molecular painArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In the rodent, the parabrachial nucleus of the pons (PbN) receives information about taste directly from the nucleus of the solitary tract (NTS). Here we examined how information about taste quality (sweet, sour, salty, and bitter) is conveyed in the PbN of awake, freely licking rats, with a focus on how this information is transformed from the incoming NTS signals. Awake rats with electrodes in the PbN had free access to a lick spout that delivered taste stimuli (5 consecutive licks; 100 mM NaCl, 10 mM citric acid, 0.01 mM quinine HCl, or 100 mM sucrose and water) or water (as a rinse) on a variable-ratio schedule. To assess temporal coding, a family of metrics that quantifies the similarity of two spike trains in terms of spike count and spike timing was used. PbN neurons (n = 49) were generally broadly tuned across taste qualities with variable response latencies. Some PbN neurons were quiescent during lick bouts, and others, some taste responsive, showed time-locked firing to the lick pattern. Compared with NTS neurons, spike timing played a larger role in signaling taste in the first 2 s of the response, contributing significantly in 78% (38/49) of PbN cells compared with 45% of NTS cells. Also, information from temporal coding increased at a faster rate as the response unfolded over time in PbN compared with NTS. Collectively, these data suggest that taste-related information from NTS converges in the PbN to enable a subset of PbN cells to carry a larger information load.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.