ArticleBMC medical research methodology2013
Facilitating accrual to cancer control and supportive care trials: the clinical research associate perspective.
Article in BMC medical research methodology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Feasibility of exercise training to address corticosteroid-induced changes in adolescents aged 10+ with lymphoma or leukemia during the first eight weeks of treatment: a pilot study.Frontiers in pediatrics · 2026Trial
- Phase II trial of subcutaneous methylnaltrexone in the treatment of severe opioid-induced constipation (OIC) in cancer patients: an exploratory study.International journal of clinical oncology · 2017Trial
- Chemotherapy-Induced Nausea and Vomiting Prophylaxis: Practice Within the Children's Oncology Group.Pediatric blood & cancer · 2016Trial
- Feasibility of Conducting a Palliative Care Randomized Controlled Trial in Children With Advanced Cancer: Assessment of the PediQUEST Study.Journal of pain and symptom management · 2015Trial
- Management of fatigue in children with cancer: a survey of pediatric hematology-oncology professionals' knowledge, attitudes, and practices in the United States and Canada.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Sharing is caring: a network collaborative approach to identify and address barriers in accessing clinical trials in adolescents and young adults with leukemia and lymphoma.Hematology. American Society of Hematology. Education Program · 2024Review
- Navigating the challenges of clinical trial professionals in the healthcare sector.Frontiers in medicine · 2024Review
- Assessment of provider perspectives on otoprotection research for children and adolescents: A Children's Oncology Group Cancer Control and Supportive Care Committee survey.Pediatric blood & cancer · 2020Article
- Barriers to Participation in Therapeutic Clinical Trials as Perceived by Community Oncologists.JCO oncology practice · 2020Article
- The Children's Oncology Group Adolescent and Young Adult Responsible Investigator Network: A New Model for Addressing Site-Level Factors Impacting Clinical Trial Enrollment.Journal of adolescent and young adult oncology · 2020Article
- Importance of incorporating measures of attitude in planning and evaluating nursing education.Journal of nursing education and practice · 2019Article
- Prevention of cisplatin-induced hearing loss in children: Informing the design of future clinical trials.Cancer medicine · 2018Article
- Searching for cures: Inner-city and rural patients' awareness and perceptions of cancer clinical trials.Contemporary clinical trials communications · 2017Article
- Nurse-Led Programs to Facilitate Enrollment to Children's Oncology Group Cancer Control Trials.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · 2016Review
- Strategies to improve success of pediatric cancer cooperative group quality of life studies: a report from the Children's Oncology Group.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundAccrual to Cancer Control and Supportive Care (CCL) studies can be challenging. Our objective was to identify facilitators and perceived barriers to successful Children's Oncology Group (COG) CCL accrual from the clinical research associate (CRA) perspective.
methodsA survey was developed that focused on the following features from the institutional perspective: (1) Components of successful accrual; (2) Barriers to accrual; (3) Institutional changes that could enhance accrual; and (4) How COG could facilitate accrual. The survey was distributed to the lead CRA at each COG site with at least 2 CCL accruals within the previous year. The written responses were classified into themes and sub-themes.
results57 sites in the United States (n = 52) and Canada (n = 5) were contacted; 34 (60%) responded. The four major themes were: (1) Staff presence and dynamics; (2) Logistics including adequate numbers of eligible patients; (3) Interests and priorities; and (4) Resources. Suggestions for improvement began at the study design/conception stage, and included ongoing training/support and increased reimbursement or credit for successful CCL enrollment.
conclusionsThe comments resulted in suggestions to facilitate CCL trials in the future. Soliciting input from key team members in the clinical trials process is important to maximizing accrual rates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.