Evidence map›Paper›PMID 24380083›Full record

ArticleJournal of neuroinfectious diseases2013

Ocular Toxoplasmosis: Controversies in Primary and Secondary Prevention.

Norman A Saffra, Carly J Seidman, Louis M Weiss

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroinfectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  6. Water related ocular diseases.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Norman A SaffraDivision of Ophthalmology, Maimonides Medical Center, Brooklyn, NY 11219, USA ; Department of Ophthalmology, New York University, New York, NY 10016, USA.
Carly J SeidmanDivision of Ophthalmology, Maimonides Medical Center, Brooklyn, NY 11219, USA ; Department of Ophthalmology, New York University, New York, NY 10016, USA.
Louis M WeissDepartments of Medicine and Pathology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA.
Maimonides Medical Center · USAlbert Einstein College of Medicine · US

Funding

Toxoplasma gondii: cyst wallR01AI095094 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WEISS, LOUIS M. · 2012 to 2016
$2.1M
NIAID NIH HHS R01 AI095094
6 · The paper itself

Abstract

Ocular toxoplasmosis is the most common cause of posterior uveitis in the United States and worldwide. It commonly follows a relapsing course with the potential for multiple adverse visual sequelae and, rarely, blindness. Both immune-competent and immune-suppressed populations can develop severe relapsing disease. There is considerable debate regarding the initial treatment of ocular toxoplasmosis in both groups, with multiple antiparasitic agents commonly used with little evidence to support any particular regimen. The precise role of corticosteroids in treatment also has yet to be rigorously defined. Secondary prevention is commonly implemented in the immune suppressed population, but there is a lack of level one evidence to support its role in immune-competent patients, though it warrants future investigation.

Indexed as

antiparasitic therapychemoprophylaxisinfectious retinal diseaseocular toxoplasmosisretinochoroiditissecondary prevention

Identifiers

PMID24380083
PMCPMC3874278
OpenAlexW2138003470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.