ArticleBioMed research international2013
The study on biocompatibility of porous nHA/PLGA composite scaffolds for tissue engineering with rabbit chondrocytes in vitro.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Research Progress and Challenges in 3D Printing of Bioceramics and Bioceramic Matrix Composites.Biomimetics (Basel, Switzerland) · 2025Review
- 3D-printed polycaprolactone combined with cartilage acellular matrix tissue engineered cartilage scaffold manufactured by low-temperature deposition manufacturing.Frontiers in bioengineering and biotechnology · 2025Article
- Significance of Viable But Non-culturable (VBNC) State in Vibrios and Other Pathogenic Bacteria: Induction, Detection and the Role of Resuscitation Promoting Factors (Rpf).Current microbiology · 2024Review
- An Overview on the Big Players in Bone Tissue Engineering: Biomaterials, Scaffolds and Cells.International journal of molecular sciences · 2024Review
- Low-temperature deposition manufacturing technology: a novel 3D printing method for bone scaffolds.Frontiers in bioengineering and biotechnology · 2023Review
- Review
- The 3D Bioprinted Scaffolds for Wound Healing.Pharmaceutics · 2022Review
- Effect of Dioxane and N-Methyl-2-pyrrolidone as a Solvent on Biocompatibility and Degradation Performance of PLGA/nHA ScaffoldsIranian biomedical journal · 2021Article
- A 3D-Printed PLCL Scaffold Coated with Collagen Type I and Its Biocompatibility.BioMed research international · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the biocompatibility of a novel nanohydroxyapatite/poly[lactic-co-glycolic acid] (nHA/PLGA) composite and evaluate its feasibility as a scaffold for cartilage tissue engineering.
methodsChondrocytes of fetal rabbit were cultured with nHA/PLGA scaffold in vitro and the cell viability was assessed by MTT assay first. Cells adhering to nHA/PLGA scaffold were then observed by inverted microscope and scanning electron microscope (SEM). The cell cycle profile was analyzed by flow cytometry.
resultsThe viability of the chondrocytes on the scaffold was not affected by nHA/PLGA comparing with the control group as it was shown by MTT assay. Cells on the surface and in the pores of the scaffold increased in a time-dependent manner. Results obtained from flow cytometry showed that there was no significant difference in cell cycle profiles between the coculture group and control (P > 0.05).
conclusionThe porous nHA/PLGA composite scaffold is a biocompatible and good kind of scaffold for cartilage tissue engineering.
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