ArticleCNS oncology2013
Decoding the cancer stem cell hypothesis in glioblastoma.
Article in CNS oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Towards non-invasive diagnosis of glioblastoma: identifying metabolic biomarkers in liquid biopsies using a ROC-based approach.Discover oncology · 2025Article
- Targeting drug resistance in glioblastoma (Review).International journal of oncology · 2024Review
- Differential expression of stem cell markers in proliferating cells in glioma.Journal of cancer research and clinical oncology · 2021Article
- Study Progression of Apelin/APJ Signaling and Apela in Different Types of Cancer.Frontiers in oncology · 2021Review
- Krüppel-like factor 9 and histone deacetylase inhibitors synergistically induce cell death in glioblastoma stem-like cells.BMC cancer · 2018Article
- Glioma Stem Cell Niches in Human Glioblastoma Are Periarteriolar.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2018Review
- Apelin, the Devil Inside Brain Tumors.Journal of experimental neuroscience · 2018Article
- Thalidomide inhibits proliferation and epithelial-mesenchymal transition by modulating CD133 expression in pancreatic cancer cells.Oncology letters · 2017Article
- Pharmacological targeting of apelin impairs glioblastoma growth.Brain : a journal of neurology · 2017Article
- Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2017Review
- β-escin selectively targets the glioblastoma-initiating cell population and reduces cell viability.Oncotarget · 2016Article
- Adhering towards tumorigenicity: altered adhesion mechanisms in glioblastoma cancer stem cells.CNS oncology · 2016Review
- Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity.Cancer research · 2016Article
- Transmembrane protein CD9 is glioblastoma biomarker, relevant for maintenance of glioblastoma stem cells.Oncotarget · 2016Article
- Stem cell niche irradiation in glioblastoma: providing a ray of hope?CNS oncology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Our understanding of the complexity of nervous system cancers has been enhanced through the incorporation of cellular heterogeneity into tumor models, with cellular subsets displaying stem cell characteristics. Advanced cancers such as glioblastoma are organized in a hierarchy with cancer stem cells at the apex. Cancer stem cells are functionally defined by their ability to self-renew and propagate tumors similar to the parental tumors from which they are derived. We will discuss advances in cancer stem cells, including the ability to prospectively isolate and interrogate cancer stem cells, by defining molecular mechanisms responsible for the tumor maintenance and growth. While the field of cancer stem cell biology is relatively young, continued elucidation of the tumor hierarchy holds promise for the development of novel patient therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.