Evidence map›Paper›PMID 24379960›Full record

ReviewIranian journal of basic medical sciences2013

Therapeutic uses and pharmacological properties of garlic, shallot, and their biologically active compounds.

Peyman Mikaili, Surush Maadirad, Milad Moloudizargari, Shahin Aghajanshakeri, Shadi Sarahroodi

Abstract readReview
In one paragraph

Review in Iranian journal of basic medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Preparing and evaluating the anti-microbial effect ofJournal of family medicine and primary care · 2024
    Article
  10. Effects of wasp (Cytotechnology · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Anticoccidial effects of tannin-based herbal formulation (Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. NOTCH Signaling in Osteosarcoma.Current issues in molecular biology · 2023
    Review

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peyman MikailiDepartment of Pharmacology, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran.
Surush MaadiradUrmia University, Faculty of Veterinary Medicine, Urmia, Iran.
Milad MoloudizargariDepartment of Pharmacology, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran.
Shahin AghajanshakeriUrmia University, Faculty of Veterinary Medicine, Urmia, Iran.
Shadi SarahroodiDepartment of Physiology and Pharmacology, School of Medicine, Qom University of Medical Sciences, Qom, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OBJECTIVE(S): Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Research in recent decades has shown widespread pharmacological effects of A. sativum and its organosulfur compounds especially Allicin. Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are organosulfur compounds such as allicin, diallyl disulphide, S-allylcysteine, and diallyl trisulfide. Allicin represents one of the most studied among these naturally occurring compounds. In addition to A. sativum, these compounds are also present in A. hirtifolium (shallot) and have been used to treat various diseases. This article reviews the pharmacological effects and traditional uses of A. sativum, A. hirtifolium, and their active constituents to show whether or not they can be further used as potential natural sources for the development of novel drugs. MATERIALS AND

methodsFor this purpose, the authors went through a vast number of sources and articles and all needed data was gathered. The findings were reviewed and classified on the basis of relevance to the topic and a summary of all effects were reported as tables.

conclusionGarlic and shallots are safe and rich sources of biologically active compounds with low toxicity. Further studies are needed to confirm the safety and quality of the plants to be used by clinicians as therapeutic agents.

Indexed as

Allium hirtifoliumAllium sativumGarlicPharmacological effectsShallotTraditional uses

Identifiers

PMID24379960
PMCPMC3874089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.