Evidence map›Paper›PMID 24379847›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2013

Prevalence of transient congenital hypothyroidism in central part of Iran.

Mahmoud Ghasemi, Mahin Hashemipour, Silva Hovsepian, Kamal Heiydari, Ali Sajadi, Rezvaneh Hadian, Marjan Mansourian, Naghme Mirshahzadeh, Marzie Dalvi

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In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

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  8. Prevalence of transient congenital hypothyroidism among neonates.Annals of medicine and surgery (2012) · 2021
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  20. Prevalence of permanent congenital hypothyroidism in isfahan-iran.International journal of preventive medicine · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mahmoud GhasemiDepartment of Pediatrics, Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran ; Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Mahin HashemipourDepartment of Pediatric Endocrinology, Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Silva HovsepianChild Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Kamal HeiydariIsfahan Health Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Ali SajadiIsfahan Health Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Rezvaneh HadianIsfahan Health Center, Isfahan University of Medical Sciences, Isfahan, Iran ; Colleague of Congenital Hypothyroidism Screening Program, Isfahan University of Medical Sciences, Isfahan, Iran.
Marjan MansourianDepartment of Biostatistics and Epidemiology, Health School, Isfahan University of Medical Sciences, Isfahan, Iran.
Naghme MirshahzadehDepartment of Pediatric Endocrinology, Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran ; Colleague of Congenital Hypothyroidism Screening Program, Isfahan University of Medical Sciences, Isfahan, Iran.
Marzie DalviColleague of Congenital Hypothyroidism Screening Program, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital hypothyroidism (CH) considered a common endocrine disorder in Iran. We report the epidemiologic findings of CH screening program in Isfahan, seven years after its development, regarding the prevalence of transient CH (TCH) and its screening properties comparing with permanent CH (PCH). MATERIALS AND

methodsIn this cross-sectional study, children with primary diagnosis of CH were studied. Considering screening and follow-up lab data and the decision of pediatric endocrinologists, the final diagnosis of TCH was determined.

resultsA total of 464,648 neonates were screened. The coverage percent of the CH screening and recall rate was 98.9 and 2.1%, respectively. Out of which, 1,990 neonates were diagnosed with primary CH. TCH was diagnosed in 1,580 neonates. The prevalence of TCH was 1 in 294 live births. 79.4% of patients with primary CH had TCH. Mean of screening (54.7 ± 59.0 in PCH vs 21.8 ± 28.9 in TCH), recall (56.5 ± 58.8 in PCH vs 36.6 ± 45.0 in TCH), and thyroid stimulating hormone (TSH) and mean of TSH before (2.0 ± 2.9 in PCH vs 1.6 ± 1.6 in TCH) and after (37.7 ± 29.5 in PCH vs 4.3 ± 1.9 in TCH) discontinuing treatment at 3 years of age was significantly higher in PCH than TCH (P < 0.0000).

conclusionThe higher rate of CH in Isfahan is mainly due to the transient form of the disease. Further studies for evaluating the role of other environmental, autoimmune and/or genetic factors in the pathophysiology of the disease is warranted.

Indexed as

Congenital hypothyroidismpermanenttransient

Identifiers

PMID24379847
PMCPMC3872610
OpenAlexW1585655543

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.