ArticleProceedings of the National Academy of Sciences of the United States of America2014
Resting-brain functional connectivity predicted by analytic measures of network communication.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 313 papers, 1 of them a synthesis that pooled it.
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Who cites it
313 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
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- N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study.The international journal of neuropsychopharmacology · 2019Trial
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- Spatial organization of AQP4 water channel expression in the human brain.Science advances · 2026Article
- Arousal-driven critical roaming reproduces human functional connectivity dynamics.PLoS biology · 2026Article
- Altered Driving Structures and Controllability Patterns of Brain Effective Networks in Mild Cognitive Impairment and Alzheimer's Disease.Brain sciences · 2026Article
- Charting higher-order models of brain function beyond pairwise interactions.Nature communications · 2026Article
- The Cerebellar Connectome.Cerebellum (London, England) · 2026Article
- Accurately modeling resting-brain functional connectivity using hypergraph neural field-Fourier deep neural network.Scientific reports · 2026Article
- Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study.BMC neuroscience · 2026Article
- Trait-Relevant Tasks Improve Personality Prediction From Structural-Functional Brain Network Coupling.Human brain mapping · 2026Article
- Structuro-Functional Differentiation and Coupling of Gyri and Sulci in the Neonatal Cortex.Human brain mapping · 2026Article
- Altered salience network structure-function integration underlies the decline in cognitive flexibility during aging.PLoS biology · 2026Article
- The structural grammar of integration and competition in the human connectome.Frontiers in computational neuroscience · 2026Article
- Coherent-resonant netting: disorder-enhanced selectivity from transient wave-like dynamics on biological connectomes.Frontiers in computational neuroscience · 2026Article
- Variation in high-amplitude events across the human lifespan.Network neuroscience (Cambridge, Mass.) · 2026Article
- Structural and functional connectivity of the brain in premature infants with non-hemorrhagic punctate white matter lesions: a graph analysis.Pediatric radiology · 2026Article
- An evaluation of the efficacy of single-echo and multi-echo fMRI denoising strategies.Network neuroscience (Cambridge, Mass.) · 2026Article
- Multidimensional structural-functional coupling uncovers network dysregulation and predicts binge-eating severity in bulimia nervosa.BMC medicine · 2025Article
253 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
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Abstract
The complex relationship between structural and functional connectivity, as measured by noninvasive imaging of the human brain, poses many unresolved challenges and open questions. Here, we apply analytic measures of network communication to the structural connectivity of the human brain and explore the capacity of these measures to predict resting-state functional connectivity across three independently acquired datasets. We focus on the layout of shortest paths across the network and on two communication measures--search information and path transitivity--which account for how these paths are embedded in the rest of the network. Search information is an existing measure of information needed to access or trace shortest paths; we introduce path transitivity to measure the density of local detours along the shortest path. We find that both search information and path transitivity predict the strength of functional connectivity among both connected and unconnected node pairs. They do so at levels that match or significantly exceed path length measures, Euclidean distance, as well as computational models of neural dynamics. This capacity suggests that dynamic couplings due to interactions among neural elements in brain networks are substantially influenced by the broader network context adjacent to the shortest communication pathways.
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