ArticleProceedings of the National Academy of Sciences of the United States of America2014
Apo-bacteriophytochromes modulate bacterial photosynthesis in response to low light.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Milestones in the development ofJournal of bacteriology · 2025Review
- Photomorphogenesis of Myxococcus macrosporus: new insights for light-regulation of cell development.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Cyanobacteriochromes from Gloeobacterales Provide New Insight into the Diversification of Cyanobacterial Photoreceptors.Journal of molecular biology · 2024Article
- Characterisation of sequence-structure-function space in sensor-effector integrators of phytochrome-regulated diguanylate cyclases.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022Article
- High-resolution crystal structures of transient intermediates in the phytochrome photocycle.Structure (London, England : 1993) · 2021Article
- Biliverdin Reductase-A Deficiency Brighten and Sensitize Biliverdin-binding Chromoproteins.Cell structure and function · 2020Article
- Phytochrome evolution in 3D: deletion, duplication, and diversification.The New phytologist · 2020Review
- Article
- Functional divergence of annotated l-isoaspartateThe Journal of biological chemistry · 2019Article
- Membrane-Bound Bacteriophytochrome-Like Complex of Phototrophic Purple Non-Sulfur Bacterium Rhodopseudomonas palustris.Doklady. Biochemistry and biophysics · 2018Article
- Article
- Near-infrared light-controlled systems for gene transcription regulation, protein targeting and spectral multiplexing.Nature protocols · 2018Article
- Molecular Basis of Bacterial Longevity.mBio · 2017Article
- Essential Genome of the Metabolically Versatile Alphaproteobacterium Rhodopseudomonas palustris.Journal of bacteriology · 2015Article
- Streptophyte phytochromes exhibit an N-terminus of cyanobacterial origin and a C-terminus of proteobacterial origin.BMC research notes · 2015Article
- Evolutionary Aspects and Regulation of Tetrapyrrole Biosynthesis in Cyanobacteria under Aerobic and Anaerobic Environments.Life (Basel, Switzerland) · 2015Review
- Eukaryotic algal phytochromes span the visible spectrum.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophytochromes (BphPs) are light-sensing regulatory proteins encoded by photosynthetic and nonphotosynthetic bacteria. This protein class has been characterized structurally, but its biological activities remain relatively unexplored. Two BphPs in the anoxygenic photosynthetic bacterium Rhodopseudomonas palustris, designated regulatory proteins RpBphP2 and RpBphP3, are configured as light-regulated histidine kinases, which initiate a signal transduction system that controls expression of genes for the low light harvesting 4 (LH4) antenna complex. In vitro, RpBphP2 and RpBphP3 respond to light quality by reversible photoconversion, a property that requires the light-absorbing chromophore biliverdin. In vivo, RpBphP2 and RpBphP3 are both required for the expression of the LH4 antenna complex under anaerobic conditions, but biliverdin requires oxygen for its synthesis by heme oxygenase. On further investigation, we found that the apo-bacteriophytochrome forms of RpBphP2 and RpBphP3 are necessary and sufficient to control LH4 expression in response to light intensity in conjunction with other signal transduction proteins. One possibility is that the system senses a reduced quinone pool generated when light energy is absorbed by bacteriochlorophyll. The biliverdin-bound forms of the BphPs have the additional property of being able to fine-tune LH4 expression in response to light quality. These observations support the concept that some bacteriophytochromes can function with or without a chromophore and may be involved in regulating physiological processes not directly related to light sensing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.