ArticleThe Pediatric infectious disease journal2014
A household-based study of acute viral respiratory illnesses in Andean children.
Article in The Pediatric infectious disease journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The risk of lower respiratory tract infection following influenza virus infection: A systematic and narrative review.Vaccine · 2018Pooled it
- Incidence of laboratory-confirmed influenza disease among infants under 6 months of age: a systematic review.BMJ open · 2017Pooled it
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- Method development and clinical validation of LAMP-CRISPR/Cas12a for rapid detection of respiratory pathogens in children.Frontiers in pediatrics · 2025Article
- Risk of Subsequent Respiratory Virus Detection After Primary Virus Detection in a Community Household Study-King County, Washington, 2019-2021.The Journal of infectious diseases · 2024Article
- Characteristics of Respiratory Syncytial Virus versus Influenza Infection in Hospitalized Patients of Peru: A Retrospective Observational Study.Tropical medicine and infectious disease · 2022Article
- Prevalence of acute respiratory infections among children in India: Regional inequalities and risk factors.Maternal and child health journal · 2022Article
- Assessing the Impact of Acute Respiratory Illnesses on the Risk of Subsequent Respiratory Illness.The Journal of infectious diseases · 2022Article
- Parainfluenza Virus Types 1-3 Infections Among Children and Adults Hospitalized With Community-acquired Pneumonia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Clinical features of parainfluenza infections among young children hospitalized for acute respiratory illness in Amman, Jordan.BMC infectious diseases · 2021Article
- Is There an Association Between Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Streptococcus pneumoniae?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Nasopharyngeal Pneumococcal Density during Asymptomatic Respiratory Virus Infection and Risk for Subsequent Acute Respiratory Illness.Emerging infectious diseases · 2019Article
- Dynamics of Colonization ofOpen forum infectious diseases · 2018Article
- A novel real-time RT-PCR assay for influenza C tested in Peruvian children.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017Article
- Article
- Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children.Open forum infectious diseases · 2017Article
- Etiology of severe pneumonia in Ecuadorian children.PloS one · 2017Observational
- Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011.Emerging infectious diseases · 2016Article
- Spatial and Temporal Spread of Acute Viral Respiratory Infections in Young Children Living in High-altitude Rural Communities: A Prospective Household-based Study.The Pediatric infectious disease journal · 2016Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 4 countries.
Funding
Abstract
backgroundFew community studies have measured the incidence, severity and etiology of acute respiratory illness (ARI) among children living at high-altitude in remote rural settings.
methodsWe conducted active, household-based ARI surveillance among children aged <3 years in rural highland communities of San Marcos, Cajamarca, Peru from May 2009 through September 2011 (RESPIRA-PERU study). ARI (defined by fever or cough) were considered lower respiratory tract infections if tachypnea, wheezing, grunting, stridor or retractions were present. Nasal swabs collected during ARI episodes were tested for respiratory viruses by real-time, reverse-transcriptase polymerase chain reaction. ARI incidence was calculated using Poisson regression.
resultsDuring 755.1 child-years of observation among 892 children in 58 communities, 4475 ARI were observed, yielding an adjusted incidence of 6.2 ARI/child-year (95% confidence interval: 5.9-6.5). Families sought medical care for 24% of ARI, 4% were classified as lower respiratory tract infections and 1% led to hospitalization. Of 5 deaths among cohort children, 2 were attributed to ARI. One or more respiratory viruses were detected in 67% of 3957 samples collected. Virus-specific incidence rates per 100 child-years were: rhinovirus, 236; adenovirus, 73; parainfluenza virus, 46; influenza, 37; respiratory syncytial virus, 30 and human metapneumovirus, 17. Respiratory syncytial virus, metapneumovirus and parainfluenza virus 1-3 comprised a disproportionate share of lower respiratory tract infections compared with other etiologies.
conclusionsIn this high-altitude rural setting with low-population density, ARI in young children were common, frequently severe and associated with a number of different respiratory viruses. Effective strategies for prevention and control of these infections are needed.
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