ReviewMedicine2014
Nocardiosis of the central nervous system: experience from a general hospital and review of 84 cases from the literature.
Review in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 176 citations in OpenAlex.
- Clinical Characteristics and Treatment Outcome of Central Nervous System Nocardiosis: A Systematic Review of Reported Cases.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022Pooled it
- Pooled it
- Nocardiosis-an uncommon infection in patients with myasthenia gravis: report of three cases and review of literature.BMJ case reports · 2020Pooled it
- Nocardiosis: A Neglected Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020Pooled it
- A 56-Year-Old Woman With Systemic Lupus Erythematosus on Trimethoprim-Sulfamethoxazole Prophylaxis Presenting With Breakthrough Nocardiosis.The American journal of case reports · 2026Article
- Nocardia brasiliensis infection causes skin abscesses around the eyes: A case-report and review of literature.IDCases · 2026Article
- Multiple IntracranialInfection and drug resistance · 2026Article
- Case Report of a Solitary Brain Abscess due toCase reports in infectious diseases · 2026Article
- PulmonaryCase reports in infectious diseases · 2026Article
- Nocardia farcinica Brain Abscess in a Glucocorticoid-Treated Patient with Giant-Cell Arteritis: A Case Report.The American journal of case reports · 2025Article
- First reported case of abdominal Nocardia pseudocyst in the setting of a ventriculoperitoneal shunt: a case report and review of literature.Journal of medical case reports · 2025Review
- Nocardiosis: A case series and literature reviewBiomedica : revista del Instituto Nacional de Salud · 2025Review
- A rare case of multiple brain abscesses caused by Nocardia abscessus co-infection with tuberculous meningitis in an immunocompetent patient.BMC infectious diseases · 2025Article
- Nocardiosis in a Patient with Nephrotic Syndrome Treated with Glucocorticoids and Tacrolimus.Internal medicine (Tokyo, Japan) · 2025Article
- An unveiling case of Nocardia pansinusitis in a patient with chronic lymphocytic leukemia: a case report.Journal of medical case reports · 2025Article
- Triple-drug antibiotic therapy for disseminated nocardial abscess in the mediastinum and brain of an immunocompetent patient: a case report.BMC infectious diseases · 2025Article
- Article
- Pulmonary nocardiosis in kidney transplant recipients: A case report and analysis of 60 published cases.IDCases · 2025Article
- First Documented Case of Pneumonia withInfection and drug resistance · 2025Article
- Case Report: Bloodstream infection withFrontiers in medicine · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central nervous system (CNS) nocardiosis is a rare disease entity caused by the filamentous bacteria Nocardia species. We present a case series of 5 patients from our hospital and a review of the cases of CNS nocardiosis reported in the literature from January 2000 to December 2011. Our results indicate that CNS nocardiosis can occur in both immunocompromised and immunocompetent individuals and can be the result of prior pulmonary infection or can exist on its own. The most common predisposing factors are corticosteroid use (54% of patients) and organ transplantation (25%). Presentation of the disease is widely variable, and available diagnostic tests are far from perfect, often leading to delayed detection and initiation of treatment. The optimal therapeutic approach is still undetermined and depends on speciation, but lower mortality and relapse rates have been reported with a combination of targeted antimicrobial treatment including trimethoprim/sulfomethoxazole (TMP-SMX) for more than 6 months and neurosurgical intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.