Evidence map›Paper›PMID 24378376›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2014

Marked repression of CFTR mRNA in the transgenic Cftr(tm1kth) mouse model.

Shaoyan Zhang, Neel K Ranganath, Daniel Skinner, David M Bedwell, Jessica A Buckley-Lanier, Eric J Sorscher, Bradford A Woodworth

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3.American journal of physiology. Gastrointestinal and liver physiology · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaoyan ZhangDepartment of Surgery, Division of Otolaryngology, University of Alabama at Birmingham, Birmingham, AL, United States; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Neel K RanganathDepartment of Surgery, Division of Otolaryngology, University of Alabama at Birmingham, Birmingham, AL, United States.
Daniel SkinnerDepartment of Surgery, Division of Otolaryngology, University of Alabama at Birmingham, Birmingham, AL, United States.
David M BedwellDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Jessica A Buckley-LanierDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, United States; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Eric J SorscherDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Bradford A WoodworthDepartment of Surgery, Division of Otolaryngology, University of Alabama at Birmingham, Birmingham, AL, United States; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: bwoodwo@hotmail.com.

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMIT GAGGAR · 2007 to 2026
$23.0M
Chloride secretagogues for acquired CFTR dysfunction in chronic rhinosinusitisK08HL107142 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WOODWORTH, BRADFORD ALAN · 2011 to 2015
$668k
NHLBI NIH HHS 1K08HL107142-03NHLBI NIH HHS K08 HL107142NIDDK NIH HHS 5P30DK072482-03NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsChloridesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorMiceMice, Inbred C57BLMice, Inbred CFTRMice, TransgenicRNA, MessengerChloridesCystic Fibrosis Transmembrane Conductance RegulatorRNA, MessengerCFTRCftr(tm1Kth) mouseChloride secretionGene expressionMurine nasal cultureNasal epitheliumPCR

Identifiers

PMID24378376
PMCPMC4300118

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.