ArticleThe Permanente journal2014
Investigation of women with postmenopausal uterine bleeding: clinical practice recommendations.
Article in The Permanente journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 77 citations in OpenAlex.
- Can machine learning predict endometrial cancer in patients with postmenopausal uterine bleeding?Przeglad menopauzalny = Menopause review · 2026Article
- Determining a Treatment Threshold Value for Endometrial Thickness in Women with Breast Cancer Receiving Tamoxifen.International journal of women's health · 2025Article
- Abnormal Uterine Bleeding: A Pictorial Review on Differential Diagnosis and Not-So-Common Cases of Interventional Radiology Management.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Assessment of paraclinical characteristics in peri- and postmenopausal bleeding women: is there a correlation between hemoglobin levels and ultrasonic indices?Journal of Taibah University Medical Sciences · 2023Article
- Preoperative Differentiation of Uterine Leiomyomas and Leiomyosarcomas: Current Possibilities and Future Directions.Cancers · 2022Review
- Potential differences in somatosensory function during premenopause and early and late postmenopause in patients with burning mouth syndrome: An observational case-control study.Journal of dental sciences · 2022Article
- Benign Histopathologic Findings of Endometrium among Perimenopausal Women presenting with Abnormal Uterine Bleeding: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2021Article
- Thickened Endometrium: When to Intervene? A Clinical Conundrum.Journal of obstetrics and gynaecology of India · 2021Review
- Risk Assessment of Endometrial Hyperplasia or Endometrial Cancer with Simplified Ultrasound-Based Scoring Systems.Diagnostics (Basel, Switzerland) · 2021Article
- Risks, Benefits, and Treatment Modalities of Menopausal Hormone Therapy: Current Concepts.Frontiers in endocrinology · 2021Review
- Cancer Prevention and Screening for Older Adults: Part 2. Interventions to Prevent and Screen for Breast, Prostate, Cervical, Ovarian, and Endometrial Cancer.Journal of the American Geriatrics Society · 2020Review
- First-time postmenopausal bleeding as a clinical marker of long-term cancer risk: A Danish Nationwide Cohort Study.British journal of cancer · 2020Article
- An Efficacious Endometrial Sampler for Screening Endometrial Cancer.Frontiers in oncology · 2019Article
- Hysteroscopic tissue removal systems for the treatment of intrauterine pathology: a systematic review and meta-analysis.Facts, views & vision in ObGyn · 2018Review
- Combined external beam radiotherapy and vaginal brachytherapy versus vaginal brachytherapy in stage I, intermediate- and high-risk cases of endometrium carcinoma.Journal of contemporary brachytherapy · 2018Article
- Vaginal foreign body mimicking cervical cancer in postmenopausal woman - case study.Przeglad menopauzalny = Menopause review · 2015Article
- Histopathological pattern of endometrial biopsies in patients with abnormal uterine bleeding in a tertiary referral hospital in Jordan.Annals of Saudi medicineArticle
- Postmenopausal Pregnancy: A Case Report.Iranian journal of nursing and midwifery researchArticle
- Challenges in the Management of Postmenopausal Uterine Artery Venous Malformation.Journal of mid-life healthArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postmenopausal uterine bleeding is defined as uterine bleeding after permanent cessation of menstruation resulting from loss of ovarian follicular activity. Bleeding can be spontaneous or related to ovarian hormone replacement therapy or to use of selective estrogen receptor modulators (eg, tamoxifen adjuvant therapy for breast carcinoma). Because anovulatory "cycles" with episodes of multimonth amenorrhea frequently precede menopause, no consensus exists regarding the appropriate interval of amenorrhea before an episode of bleeding that allows for the definition of postmenopausal bleeding. The clinician faces the possibility that an underlying malignancy exists, knowing that most often the bleeding comes from a benign source. Formerly, the gold-standard clinical investigation of postmenopausal uterine bleeding was institution-based dilation and curettage, but there now exist office-based methods for the evaluation of women with this complaint. Strategies designed to implement these diagnostic methods must be applied in a balanced way considering the resource utilization issues of overinvestigation and the risk of missing a malignancy with underinvestigation. Consequently, guidelines and recommendations were developed to consider these issues and the diverse spectrum of practitioners who evaluate women with postmenopausal bleeding. The guideline development group determined that, for initial management of spontaneous postmenopausal bleeding, primary assessment may be with either endometrial sampling or transvaginal ultrasonography, allowing patients with an endometrial echo complex thickness of 4 mm or less to be managed expectantly. Guidelines are also provided for patients receiving selective estrogen receptor modulators or hormone replacement therapy, and for an endometrial echo complex with findings consistent with fluid in the endometrial cavity.�
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