Evidence map›Paper›PMID 24377391›Full record

ArticleGigaScience2013

Galaxy tools to study genome diversity.

Oscar C Bedoya-Reina, Aakrosh Ratan, Richard Burhans, Hie Lim Kim, Belinda Giardine, Cathy Riemer, Qunhua Li, Thomas L Olson, Thomas P Loughran, Bridgett M Vonholdt and 3 more

Abstract read
In one paragraph

Article in GigaScience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Genomic Variants Among ThreatenedG3 (Bethesda, Md.) · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. GigaDB: promoting data dissemination and reproducibility.Database : the journal of biological databases and curation · 2014
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Oscar C Bedoya-Reina
Aakrosh Ratan
Richard Burhans
Hie Lim Kim
Belinda Giardine
Cathy Riemer
Qunhua Li
Thomas L Olson
Thomas P Loughran
Bridgett M Vonholdt
George H Perry
Stephan C Schuster
Webb MillerCenter for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, PA 16802, USA. webb@bx.psu.edu.

Funding

Cancer Research Training Program: From Molecular Mechanisms to Therapeutic StrategiesT32CA009109 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Andrew Carl Dudley, Melanie R Rutkowski · 1985 to 2026
$13.9M
Statistical methods for improving reproducibility and utility of sequencing dataR01GM109453 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI LI, QUNHUA · 2013 to 2022
$2.3M
NCI NIH HHS T32 CA009109NIGMS NIH HHS R01 GM109453
6 · The paper itself

Abstract

backgroundIntra-species genetic variation can be used to investigate population structure, selection, and gene flow in non-model vertebrates; and due to the plummeting costs for genome sequencing, it is now possible for small labs to obtain full-genome variation data from their species of interest. However, those labs may not have easy access to, and familiarity with, computational tools to analyze those data.

resultsWe have created a suite of tools for the Galaxy web server aimed at handling nucleotide and amino-acid polymorphisms discovered by full-genome sequencing of several individuals of the same species, or using a SNP genotyping microarray. In addition to providing user-friendly tools, a main goal is to make published analyses reproducible. While most of the examples discussed in this paper deal with nuclear-genome diversity in non-human vertebrates, we also illustrate the application of the tools to fungal genomes, human biomedical data, and mitochondrial sequences.

conclusionsThis project illustrates that a small group can design, implement, test, document, and distribute a Galaxy tool collection to meet the needs of a particular community of biologists.

Identifiers

PMID24377391
PMCPMC3877877

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.