Evidence map›Paper›PMID 24376473›Full record

ArticleCellular and molecular bioengineering2013

Highly Transient Molecular Interactions Underlie the Stability of Kinetochore-Microtubule Attachment During Cell Division.

Anatoly V Zaytsev, Fazly I Ataullakhanov, Ekaterina L Grishchuk

Abstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Anatoly V ZaytsevPhysiology Department, Perelman School of Medicine, University of Pennsylvania, 3700 Hamilton Walk, A401 Richards Building, Philadelphia, PA 19104, USA.
Fazly I AtaullakhanovCenter for Theoretical Problems of Physicochemical Pharmacology, RAS, Moscow, Russia, 119991 ; Physics Department, Moscow State University, Moscow, Russia, 119899 ; Laboratory of Biophysics, Federal Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia, 117198.
Ekaterina L GrishchukPhysiology Department, Perelman School of Medicine, University of Pennsylvania, 3700 Hamilton Walk, A401 Richards Building, Philadelphia, PA 19104, USA.
University of Pennsylvania · USCenter for Theoretical Problems of Physicochemical Pharmacology · RU

Funding

MICROTUBULE POLYMERIZATION AND DYNAMICS IN VIVOR01GM033787 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI MCINTOSH, JOHN RICHARD · 1985 to 2017
$6.5M
Coupling kinetochore microtubule dynamics to chromosome motionR01GM098389 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GRISHCHUK, EKATERINA L · 2012 to 2020
$3.1M
NIGMS NIH HHS R01 GM033787NIGMS NIH HHS R01 GM098389
6 · The paper itself

Abstract

Chromosome segregation during mitosis is mediated by spindle microtubules that attach to chromosomal kinetochores with strong yet labile links. The exact molecular composition of the kinetochore-microtubule interface is not known but microtubules are thought to bind to kinetochores

Indexed as

AffinityCooperativityMathematical modelingMicrotubule bindingPhosphorylation

Identifiers

PMID24376473
PMCPMC3873142
OpenAlexW1973637282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.