Evidence map›Paper›PMID 24376354›Full record

SynthesisInternational journal of nanomedicine2014

Clinical implications of calcifying nanoparticles in dental diseases: a critical review.

Mohammed S Alenazy, Hezekiah A Mosadomi

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of nanomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mohammed S AlenazyRestorative Dentistry Department, Riyadh, Saudi Arabia.
Hezekiah A MosadomiOral and Maxillofacial Pathology Department, Riyadh, Saudi Arabia ; Research Center, Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia.
Riyadh Elm University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnknown cell-culture contaminants were described by Kajander and Ciftçioğlu in 1998. These contaminants were called nanobacteria initially and later calcifying nanoparticles (CNPs). Their exact nature is unclear and controversial. CNPs have unique and unusual characteristics, which preclude placing them into any established evolutionary branch of life.

aimThe aim of this systematic review was to assess published data concerning CNPs since 1998 in general and in relation to dental diseases in particular. MATERIALS AND

methodsThe National Library of Medicine (PubMed) and Society of Photographic Instrumentation Engineers (SPIE) electronic and manual searches were conducted. Nanobacteria and calcifying nanoparticles were used as keywords. The search yielded 135 full-length papers. Further screening of the titles and abstracts that followed the review criteria resulted in 43 papers that met the study aim.

conclusionThe review showed that the existence of nanobacteria is still controversial. Some investigators have described a possible involvement of CNPs in pulpal and salivary gland calcifications, as well as the possible therapeutic use of CNPs in the treatment of cracked and/or eroded teeth.

Indexed as

AnimalsCalcifying NanoparticlesCalcinosisHumansModels, BiologicalStomatognathic DiseasesToothCalcifying Nanoparticlescalcifying nanoparticlesenamel repairnanobacteriapulp stonesialolith

Identifiers

PMID24376354
PMCPMC3865087
OpenAlexW2054219523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.