ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2014
The periductal channels of the endolymphatic duct, hydrodynamic implications.
Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Contrast Agent Uptake in Endolymphatic Sac and Duct: Inverse Relation to Endolymphatic Hydrops.The Laryngoscope · 2025Article
- Comparison of vestibular aqueduct visualization on computed tomography and magnetic resonance imaging in patients with Ménière's disease.BMC medical imaging · 2024Article
- Temporal bone marrow of the rat and its connections to the inner ear.Frontiers in neurology · 2024Article
- Endolymphatic Duct and Sac Decompression: A New Life for an Old Technique.The journal of international advanced otology · 2023Article
- Comparison of radiological abnormalities between the jugular bulb and the vestibular aqueduct in patients with Ménière's disease.Frontiers in neurology · 2023Article
- Anatomical variation of inner ear may be a predisposing factor for unilateral Ménière's disease rather than for ipsilateral delayed endolymphatic hydrops.European radiology · 2022Article
- Endolymphatic duct and sac decompression: A new technique for Ménière's disease treatment.Surgical neurology international · 2022Article
- FGF23 and its role in X-linked hypophosphatemia-related morbidity.Orphanet journal of rare diseases · 2019Review
- Claudin expression in the rat endolymphatic duct and sac - first insights into regulation of the paracellular barrier by vasopressin.Scientific reports · 2017Article
- Post Hybrid Cochlear Implant Hearing Loss and Endolymphatic Hydrops.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2016Article
- Endolymphatic duct blockage: quality of life assessment of a novel surgical technique for Ménière disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
- Treatment of ear and bone disease in the Phex mouse mutant with dietary supplementation.American journal of otolaryngologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo describe the anatomy of a small network of channels surrounding the human endolymphatic duct. STUDY
designArchival temporal bone sections and a surgical specimen were studied using a variety of techniques.
settingTemporal bone laboratory of the House Research Institute. SUBJECTS AND
methodsArchival temporal bone sections were examined by light microscopy, 3D reconstruction, and immunohistochemical labeling. A surgical specimen was examined using electron microscopy. Sections from temporal bones with blocked endolymphatic ducts or amputated sacs were examined for the manifestations of endolymphatic hydrops.
resultsPeri-endolymphatic duct channels were found to extend from the proximal cisternal part of the endolymphatic sac to the supporting tissue of the saccule and utricle. Tissue in the channels, as seen by conventional and electron microscopy, is continuous with and identical with the tissue surrounding the endolymphatic duct. Tissue in the channels labels with the S100 antibody similar to the spiral ligament and supporting tissue of the vestibular end organs and suggests a neural crest origin, as did the presence of melanocytes. Obstruction of the endolymphatic duct resulted in endolymphatic hydrops whereas amputation of the sac did not.
conclusionEndolymph is probably absorbed in the endolymphatic duct. The peri-endolymphatic duct channels that extend from the proximal sac to the supporting tissue of the saccule label with the S100 antibody and contain melanocytes suggest a neural crest origin and involvement in fluid and potassium hydrodynamics similar to those described for the similarly staining spiral ligament of the cochlea.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.