Evidence map›Paper›PMID 24376110›Full record

ReviewGenesis (New York, N.Y. : 2000)2014

Every which way--nanos gene regulation in echinoderms.

Nathalie Oulhen, Gary M Wessel

Abstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Comparative Analysis ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nathalie OulhenDepartment of Molecular and Cell Biology and Biochemistry, Brown University, Providence, Rhode Island.
Gary M Wessel

Funding

Post-translational Regulation of Germline DeterminantsR01HD028152 · NICHD · BROWN UNIVERSITY · PI WESSEL, GARY M · 1997 to 2016
$3.9M
NICHD NIH HHS R01 HD028152
6 · The paper itself

Abstract

Nanos is an essential factor of germ line success in all animals tested. This gene encodes a Zn-finger RNA-binding protein that in complex with its partner pumilio binds to and changes the fate of several known transcripts. We summarize here the documented functions of Nanos in several key organisms, and then emphasize echinoderms as a working model for how nanos expression is regulated. Nanos presence outside of the target cells is often detrimental to the animal, and in sea urchins, nanos expression appears to be regulated at every step of transcription, and post-transcriptional activity, making this gene product exciting, every which way.

Indexed as

AnimalsCell LineageDrosophila ProteinsEchinodermataGene Expression RegulationGerm CellsRNA-Binding ProteinsSpecies SpecificityDrosophila Proteinsnos protein, Drosophilapum protein, DrosophilaRNA-Binding Proteinsgerm lineprimordial germ cellssea starsea urchinstarfish

Identifiers

PMID24376110
PMCPMC3965602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.