Evidence map›Paper›PMID 24376064›Full record

ArticleNeurorehabilitation and neural repair2014

Presence of Motor-Intentional Aiming Deficit Predicts Functional Improvement of Spatial Neglect With Prism Adaptation.

Kelly M Goedert, Peii Chen, Raymond C Boston, Anne L Foundas, A M Barrett

Registry-linked trialAbstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04966000 (Development of a Neuroimaging Biomarker to Identify Optimal Candidates for Prism Adaptation Treatment), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04966000 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Development of a Neuroimaging Biomarker to Identify Optimal Candidates for Prism Adaptation Treatment

TypeinterventionalSponsorUniversity of UtahRan2023 to 2024Enrolled0ConditionsPerceptual Disorders, Stroke, BiomarkerArmsPrism Adaptation Therapy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Spatial Neglect and Anosognosia After Right Brain Stroke.Continuum (Minneapolis, Minn.) · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Update on the Clinical Approach to Spatial Neglect.Current neurology and neuroscience reports · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Kelly M GoedertSeton Hall University, South Orange, NJ, USA kelly.goedert@shu.edu.
Peii ChenKessler Foundation, West Orange, NJ, USA Rutgers New Jersey Medical School, Newark, NJ, USA.
Raymond C BostonUniversity of Pennsylvania, Philadelphia, PA, USA.
Anne L FoundasUniversity of Missouri-Kansas City, MO, USA.
A M BarrettKessler Foundation, West Orange, NJ, USA Rutgers New Jersey Medical School, Newark, NJ, USA Kessler Institute for Rehabilitation, West Orange, NJ, USA.
Kessler Institute for Rehabilitation · USRutgers New Jersey Medical SchoolSeton Hall University · USUniversity of Missouri–Kansas City · USUniversity of Pennsylvania · US

Funding

Building a science for treatment of spatial neglectR01NS055808 · NINDS · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2008 to 2011
$1.6M
Spatial neglect and bias in near and far spaceK02NS047099 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BARRETT, A. M. · 2004 to 2008
$746k
Mentoring translational cognitive science for stroke recoveryK24HD062647 · NICHD · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2010 to 2014
$695k
NICHD NIH HHS K24 HD062647NINDS NIH HHS K02 NS047099NINDS NIH HHS R01 NS055808
6 · The paper itself

Abstract

unlabelledBackground Spatial neglect is a debilitating disorder for which there is no agreed on course of rehabilitation. The lack of consensus on treatment may result from systematic differences in the syndrome's characteristics, with spatial cognitive deficits potentially affecting perceptual-attentional "Where" or motor-intentional "Aiming" spatial processing. Heterogeneity of response to treatment might be explained by different treatment impacts on these dissociated deficits: prism adaptation, for example, might reduce Aiming deficits without affecting Where spatial deficits.

objectiveHere, we tested the hypothesis that classifying patients by their profile of Where-versus-Aiming spatial deficit would predict response to prism adaptation and specifically that patients with Aiming bias would have better recovery than those with isolated Where bias. Methods We classified the spatial errors of 24 subacute right stroke survivors with left spatial neglect as (1) isolated Where bias, (2) isolated Aiming bias, or (3) both. Participants then completed 2 weeks of prism adaptation treatment. They also completed the Behavioral Inattention Test and Catherine Bergego Scale (CBS) tests of neglect recovery weekly for 6 weeks. Results As hypothesized, participants with only Aiming deficits improved on the CBS, whereas those with only Where deficits did not improve. Participants with both deficits demonstrated intermediate improvement. Conclusion These results support behavioral classification of spatial neglect patients as a potential valuable tool for assigning targeted, effective early rehabilitation.

Indexed as

Adaptation, PhysiologicalAdultAgedAged, 80 and overAttentionFemaleHumansMaleMiddle AgedPerceptual DisordersRecovery of FunctionSpace PerceptionStrokeStroke RehabilitationTreatment Outcomelesion mappingmotor-intentionalprism adaptationspatial cognitionspatial neglectstroke rehabilitation

Identifiers

PMID24376064
PMCPMC4074266
OpenAlexW2054047984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.