Evidence map›Paper›PMID 24375979›Full record

ReviewWiley interdisciplinary reviews. RNA

Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells.

Zhongwei Li, Sulochan Malla, Brian Shin, James M Li

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Targeting RNA oxidation by ISG20-mediated degradation is a potential therapeutic strategy for acute kidney injury.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  7. A potential novel therapy addressing RNA oxidative damage in AKI.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Role of RNA Oxidation in Neurodegenerative Diseases.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs.Oxidative medicine and cellular longevity · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhongwei LiDepartment of Biomedical Science, Florida Atlantic University, Boca Raton, FL, USA.
Sulochan Malla
Brian Shin
James M Li
Florida Atlantic University · US

Funding

RNA quality control against oxidative damageR15GM097693 · NIGMS · FLORIDA ATLANTIC UNIVERSITY · PI LI, ZHONGWEI · 2011 to 2011
$318k
NIGMS NIH HHS GM097693NIGMS NIH HHS R15 GM097693
6 · The paper itself

Abstract

Oxidation is probably the most common type of damage that occurs in cellular RNA. Oxidized RNA may be dysfunctional and is implicated in the pathogenesis of age-related human diseases. Cellular mechanisms controlling oxidized RNA have begun to be revealed. Currently, a number of ribonucleases and RNA-binding proteins have been shown to reduce oxidized RNA and to protect cells under oxidative stress. Although information about how these factors work is still very limited, we suggest several mechanisms that can be used to minimize oxidized RNA in various organisms.

Indexed as

Oxidative StressAnimalsDNA-(Apurinic or Apyrimidinic Site) LyaseHumansOxidation-ReductionPolyribonucleotide NucleotidyltransferaseRNARNA StabilityDNA-(Apurinic or Apyrimidinic Site) LyasePolyribonucleotide NucleotidyltransferaseRNA

Identifiers

PMID24375979
PMCPMC3991771
OpenAlexW1842113995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.