Evidence map›Paper›PMID 24375945›Full record

ArticleMolecular nutrition & food research2014

Voluntary exercise and green tea enhance the expression of genes related to energy utilization and attenuate metabolic syndrome in high fat fed mice.

Sudathip Sae-Tan, Connie J Rogers, Joshua D Lambert

Abstract read
In one paragraph

Article in Molecular nutrition & food research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Review
  3. Alpha-Linolenic Acid fromJournal of agricultural and food chemistry · 2025
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  15. Silkworm pupae powder ingestion increases fat metabolism in swim-trained rats.Journal of exercise nutrition & biochemistry · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sudathip Sae-TanDepartment of Food Science, The Pennsylvania State University, University Park, PA, USA.
Connie J Rogers
Joshua D Lambert
Pennsylvania State University · US

Funding

Fatty Liver Preventive Effects and High Dose Hepatotoxicity of Tea PolyphenolsR01AT004678 · NCCIH · PENNSYLVANIA STATE UNIVERSITY, THE · PI LAMBERT, JOSHUA D · 2009 to 2013
$1.7M
NCCIH NIH HHS AT004678NCCIH NIH HHS R01 AT004678
6 · The paper itself

Abstract

Obesity and metabolic syndrome are growing public health problems. We investigated the effects of decaffeinated green tea extract (GTE) and voluntary running exercise (Ex) alone or in combination against obesity and metabolic syndrome in high fat (HF) fed C57BL/6J mice. After 16 wk, GTE + Ex treatment reduced final body mass (27.1% decrease) and total visceral fat mass (36.6% decrease) compared to HF-fed mice. GTE + Ex reduced fasting blood glucose (17% decrease), plasma insulin (65% decrease), and insulin resistance (65% decrease) compared to HF-fed mice. GTE or Ex alone had less significant effects. In the skeletal muscle, the combination of Ex and GTE increased the expression of peroxisome proliferator-activated receptor-γ coactivator-1α (Ppargc1a), mitochondrial NADH dehydrogenase 5 (mt-Nd5), mitochondrial cytochrome b (mt-Cytb), and mitochondrial cytochrome c oxidase III (mt-Co3). An increase in hepatic expression of peroxisome proliferator-activated receptor-α (Ppara) and liver carnitine palmitoyl transferase-1α (Cpt1a) and a decrease in hepatic expression of stearoyl-CoA desaturase 1 (Scd1) mRNA was observed in GTE + Ex mice. GTE + Ex was more effective than either treatment alone in reducing diet-induced obesity. These effects are due in part to modulation of genes related to energy metabolism and de novo lipogenesis.

Indexed as

Diet, High-FatPhysical Conditioning, AnimalAnimalsCarnitine O-PalmitoyltransferaseEnergy MetabolismInsulin ResistanceLiverMaleMetabolic SyndromeMiceMice, Inbred C57BLMuscle, SkeletalNADH DehydrogenaseObesityPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaRNA, MessengerCarnitine O-PalmitoyltransferaseNADH DehydrogenasePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseRNA, MessengerScd1 protein, mouseStearoyl-CoA DesaturaseTeaTranscription FactorsCatechinsFatty acid oxidationGreen teaMitochondrial biogenesisVoluntary exercise

Identifiers

PMID24375945
PMCPMC13158972
OpenAlexW2034204854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.