Evidence map›Paper›PMID 24375570›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2014

A noninvasive handheld assistive device to accommodate essential tremor: a pilot study.

Anupam Pathak, John A Redmond, Michael Allen, Kelvin L Chou

Abstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Tremor Control Devices for Essential Tremor: A Systematic Literature Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019
    Pooled it
  2. An Acute Randomized Controlled Trial of Noninvasive Peripheral Nerve Stimulation in Essential Tremor.Neuromodulation : journal of the International Neuromodulation Society · 2019
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Emerging strategies in the management of essential tremor.Therapeutic advances in neurological disorders · 2017
    Review
  13. Article
  14. Voluntary-Driven Elbow Orthosis with Speed-Controlled Tremor Suppression.Frontiers in bioengineering and biotechnology · 2016
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anupam PathakLift Labs Design, San Francisco, California, USA.
John A Redmond
Michael Allen
Kelvin L Chou

Funding

Michigan Parkinson's Disease Clinical CenterU10NS044504 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHOU, KELVIN L · 2002 to 2013
$785k
Development of an Active Cancellation of Tremor (ACT) System for Human AssistanceR44NS070438 · NINDS · LYNX DESIGN · PI PATHAK, ANUPAM · 2011 to 2012
$673k
NINDS NIH HHS 5R44NS070438NINDS NIH HHS R44 NS070438NINDS NIH HHS U10 NS044504
6 · The paper itself

Abstract

backgroundWe explored whether a noninvasive handheld device using Active Cancellation of Tremor (ACT) technology could stabilize tremor-induced motion of a spoon in individuals with essential tremor (ET).

methodsFifteen ET subjects (9 men, 6 women) performed 3 tasks with the ACT device turned on and off. Tremor severity was rated with the Fahn-Tolosa-Marin Tremor Rating Scale (TRS). Subjective improvement was rated by subjects with the Clinical Global Impression Scale (CGI-S). Tremor amplitude was measured using device-embedded accelerometers in 11 subjects.

resultsTRS scores improved with ACT on (versus off) in all 3 tasks: holding (1.00 ± 0.76 vs. 0.27 ± 0.70; P = 0.016), eating (1.47 ± 1.06 vs. 0.13 ± 0.64; P = 0.001), and transferring (1.33 ± 0.82 vs. 0.27 ± 0.59; P = 0.001). CGI-S improved with eating and transferring, but not the holding task. Accelerometer measurements demonstrated 71% to 76% reduction in tremor with the ACT device on.

conclusionsThis noninvasive handheld ACT device can reduce tremor amplitude and severity for eating and transferring tasks in individuals with ET.

Indexed as

Self-Help DevicesAccelerometryAgedAged, 80 and overEssential TremorFemaleHumansMaleMiddle AgedMovementPilot ProjectsPsychomotor PerformanceSeverity of Illness Indexessential tremornoninvasive devicetreatment

Identifiers

PMID24375570
PMCPMC4156033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.