ArticleJournal of clinical laboratory analysis2014
Serum 25-hydroxyvitamin D level and extent and complexity of coronary artery disease.
Article in Journal of clinical laboratory analysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association Between the Circulating Level of 25-Hydroxyvitamin D and Clinical Results After Cardiac Surgery: A Meta-Analysis and Systematic Review.Frontiers in cardiovascular medicine · 2021Pooled it
- Association Between Hypovitaminosis D and Angiographic Severity of Coronary Artery Disease in Bangladesh.Cureus · 2026Article
- New Modifiable Risk Factors Influencing Coronary Artery Disease Severity.International journal of molecular sciences · 2024Review
- Vitamin D and macrophage polarization in epicardial adipose tissue of atherosclerotic swine.PloS one · 2018Article
- Dietary Supplements and Cardiovascular Diseases.International journal of preventive medicine · 2018Review
- Vitamin D Deficiency Accelerates Coronary Artery Disease Progression in Swine.Arteriosclerosis, thrombosis, and vascular biology · 2016Article
- Vitamin D Supplementation Reduces Intimal Hyperplasia and Restenosis following Coronary Intervention in Atherosclerotic Swine.PloS one · 2016Article
- Interplay of vitamin D, erythropoiesis, and the renin-angiotensin system.BioMed research international · 2015Review
- Vitamin D Deficiency is not Associated with Higher Levels of SYNTAX Score.Brazilian journal of cardiovascular surgeryArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are limited number of studies about relationship between serum vitamin D level and presence and severity of coronary artery disease (CAD). We assessed the relationship between the extent and complexity of CAD assessed by SYNTAX score and 25-hydroxyvitamin D level in patients with stable CAD.
methodsIn the study, 209 consecutive patients with stable CAD (age: 63.1 ± 10.0 years) and 102 healthy control subjects (age 61.3 ± 13.7 years) were included. Serum 25-hydroxyvitamin D was measured using a direct competitive chemiluminescent immunoassay and other biochemical markers were measured in all subjects. All subjects underwent coronary angiography and SS was calculated.
resultsThe mean serum 25-hydroxyvitamin D level of CAD group was lower than the control group (P < 0,001). Multivariate regression analysis showed that serum 25-hydroxyvitamin D level was independently associated with SYNTAX score (β = -0.396, P < 0.001), hypertension (β = -0.183, P = 0.003), high sensitive C-reactive protein (β = -0.141, P = 0.014), and body mass index (β = -0.135, P = 0.023) in patient group.
conclusion25-Hydroxyvitamin D level was associated with extent and complexity of CAD. 25-Hydroxyvitamin D may play a role in pathogenesis and severity of coronary atherosclerosis.
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Registered trials
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