Evidence map›Paper›PMID 24375201›Full record

ArticleEuropean journal of applied physiology2014

Vascular adaptations to low-load resistance training with and without blood flow restriction.

Christopher A Fahs, Lindy M Rossow, Robert S Thiebaud, Jeremy P Loenneke, Daeyeol Kim, Takashi Abe, Travis W Beck, Daniel L Feeback, Debra A Bemben, Michael G Bemben

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in European journal of applied physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03272737 nacompletednot on this mapstarted 2018, after this paper: background citation

Effect of Low Intensity Strength Training Combined With Moderate Blood Flow Restriction on Muscle Vasodilatation and Arterial Stiffness in Elders With Low Gait Velocity.

TypeinterventionalSponsorHospital Israelita Albert EinsteinRan2018 to 2022Enrolled26ConditionsFrail Elderly SyndromeArms1RM Test, Speed gait test, Venous occlusion plethysmography protocol, Measurement of Arterial Stiffness - Pulse Wave Analysis and Velocity, Isometric handgrip exercise protocol
NCT06596304 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparing Macro- and Microvascular Responses to Acute Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults: a Parallel Group Crossover Randomized Trial

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2024 to 2025Enrolled52ConditionsAgeing, Blood Flow RestrictionArmsLow intensity-resistance training with lower limb blood flow restriction, High Intensity Resistance Training
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Review
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  10. Effects of blood flow restriction (BFR) with resistance exercise on musculoskeletal health in older adults: a narrative review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2022
    Review
  11. Review
  12. Article
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  14. The Systemic Effects of Blood Flow Restriction Training: A Systematic Review.International journal of sports physical therapy · 2021
    Article
  15. Review
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  18. Low intensity resistance exercise training with blood flow restriction: insight into cardiovascular function, and skeletal muscle hypertrophy in humans.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2015
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christopher A FahsFitchburg State University, 160 Pearl Street, Fitchburg, MA, 01420, USA, cfahs1@fitchburgstate.edu.
Lindy M Rossow
Robert S Thiebaud
Jeremy P Loenneke
Daeyeol Kim
Takashi Abe
Travis W Beck
Daniel L Feeback
Debra A Bemben
Michael G Bemben
University of Oklahoma · USFitchburg State University · USIndiana University Bloomington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the effects of low-load knee extensor training to fatigue with and without blood flow restriction (BFR) on calf vascular conductance, calf venous compliance, and peripheral arterial stiffness in middle-aged individuals.

methodsEleven men (55 ± 8 years) and five post-menopausal women (57 ± 5 years) completed 6 weeks of unilateral knee extensor training with one limb exercising with BFR (BFR limb) and the contralateral limb exercising without BFR (free flow, FF limb). Before and after the training, femoral pulse wave velocity (PWV), calf blood flow (normalized as conductance), and calf venous compliance were measured in each limb.

resultsPWV increased following training in both limbs (main effect of time, p = 0.036; BFR limb 8.9 ± 0.8 vs. 9.5 ± 0.9 m/s, FF limb 9.0 ± 1.2 vs. 9.0 ± 1.1; Pre vs. Post). Calf blood flow increased (p = 0.026) in the FF limb (25.0 ± 7.0 vs. 31.8 ± 12.0 flow/mmHg; Pre vs. Post) but did not change (p = 0.831) in the BFR limb (29.1 ± 11.3 vs. 28.7 ± 11.5 flow/mmHg; Pre vs. Post). Calf venous compliance did not change in either limb following training.

conclusionsThese results suggest low-load BFR resistance training to fatigue elicits small increases in peripheral arterial stiffness without eliciting concomitant changes in venous compliance. In addition, unlike low-load knee extensor training without BFR, training with BFR did not enhance calf blood flow.

Indexed as

Adaptation, PhysiologicalRegional Blood FlowResistance TrainingAdultFemaleHumansLegMaleMiddle AgedVascular Stiffness

Identifiers

PMID24375201
OpenAlexW2095021231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.